title: Benchmarking of different molecular docking methods for protein-peptide docking.
creator: Agrawal, Piyush
creator: Singh, Harinder
creator: Srivastava, Hemant Kumar
creator: Singh, Sandeep
creator: Kishore, Gaurav
creator: Raghava, G.P.S.
subject: QR Microbiology
description: Molecular docking studies on protein-peptide interactions are a challenging and time-consuming task because peptides are generally more flexible than proteins and tend to adopt numerous conformations. There are several benchmarking studies on protein-protein, protein-ligand and nucleic acid-ligand docking interactions. However, a series of docking methods is not rigorously validated for protein-peptide complexes in the literature. Considering the importance and wide application of peptide docking, we describe benchmarking of 6 docking methods on 133 protein-peptide complexes having peptide length between 9 to 15 residues. The performance of docking methods was evaluated using CAPRI parameters like FNAT, I-RMSD, L-RMSD.
publisher: Springer Nature
date: 2019-02-04
type: Article
type: PeerReviewed
relation: https://bmcbioinformatics.biomedcentral.com/articles/10.1186/s12859-018-2449-y
identifier:   Agrawal, Piyush and Singh, Harinder and Srivastava, Hemant Kumar and Singh, Sandeep and Kishore, Gaurav and Raghava, G.P.S.  (2019) Benchmarking of different molecular docking methods for protein-peptide docking.  BMC bioinformatics, 19 (Suppl ).  p. 426.  ISSN 1471-2105     
relation: http://crdd.osdd.net/open/2175/