%A Piyush Agrawal
%A Harinder Singh
%A Hemant Kumar Srivastava
%A Sandeep Singh
%A Gaurav Kishore
%A G.P.S. Raghava
%O Open Access
%J BMC bioinformatics
%T Benchmarking of different molecular docking methods for protein-peptide docking.
%X Molecular docking studies on protein-peptide interactions are a challenging and time-consuming task because peptides are generally more flexible than proteins and tend to adopt numerous conformations. There are several benchmarking studies on protein-protein, protein-ligand and nucleic acid-ligand docking interactions. However, a series of docking methods is not rigorously validated for protein-peptide complexes in the literature. Considering the importance and wide application of peptide docking, we describe benchmarking of 6 docking methods on 133 protein-peptide complexes having peptide length between 9 to 15 residues. The performance of docking methods was evaluated using CAPRI parameters like FNAT, I-RMSD, L-RMSD.
%N Suppl 
%K ATTRACT; Benchmark; CAPRI; FRODOCK; Hex; PatchDock; Protein-peptide docking; ZDOCK; pepATTRACT
%P 426
%V 19
%D 2019
%I Springer Nature
%L open2175