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primary topic: Purification, biochemical characterization and self-assembled structure of a fengycin-like antifungal peptide from Bacillus thuringiensis strain SM1.

Purification, biochemical characterization and self-assembled structure of a fengycin-like antifungal peptide from Bacillus thuringiensis strain SM1.
type: AcademicArticle
type: Article
abstract: An antifungal lipopeptide fengycin, producing strain SM1 was isolated from farm land soil sample and identified as Bacillus thuringiensis strain SM1 by using 16S rDNA analysis. Fengycin detected in the culture extract was further purified using HPLC and showed a molecular mass of 1492.8 Da by MALDI-TOF-MS analysis. Purified fengycin was allowed to construct their self-assembled structure onto a hydrophobic surface showing a clear improvement of antibacterial activity. In self-assembly, fengycin adapts a spherical micelle core shell like structure. Self-assembled fengycin may be a successful antimicrobial compound modifying its action from confined antifungal function. Besides it can open up a new area of research in supramolecular lipopeptide based compound making. This can revealed the mode of action of this unique self-assembled structure to fully evaluate its potential for use as an antimicrobial drug to control the emergence of bacterial infection.
date: 2013
volume: 4
is part of: Frontiers in microbiology
status: peerReviewed
status: published
author list: authors
type: EPrint
type: ArticleEPrint
is part of: repository
subject: QR Microbiology

Frontiers Media
type: Organization

Frontiers in microbiology
type: Collection
issn: 1664302X

Santi M Mandal
type: Person
given name: Santi M
family name: Mandal

Anupam Roy
type: Person
given name: Anupam
family name: Roy

Debarati Paul
type: Person
given name: Debarati
family name: Paul

Denial Mahata
type: Person
given name: Denial
family name: Mahata

Octavio L Franco
type: Person
given name: Octavio L
family name: Franco

Suresh Korpole
type: Person
given name: Suresh
family name: Korpole

HTML Summary of #2453 Purification, biochemical characterization and self-assembled structure of a fengycin-like antifungal peptide from Bacillus thuringiensis strain SM1.
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primary topic: Purification, biochemical characterization and self-assembled structure of a fengycin-like antifungal peptide from Bacillus thuringiensis strain SM1.

QR Microbiology
type: Concept