<> "The repository administrator has not yet configured an RDF license."^^ . <> . . . "Prediction of beta-turns in proteins from multiple alignment using neural network."^^ . "A neural network-based method has been developed for the prediction of beta-turns in proteins by using multiple sequence alignment. Two feed-forward back-propagation networks with a single hidden layer are used where the first-sequence structure network is trained with the multiple sequence alignment in the form of PSI-BLAST-generated position-specific scoring matrices. The initial predictions from the first network and PSIPRED-predicted secondary structure are used as input to the second structure-structure network to refine the predictions obtained from the first net. A significant improvement in prediction accuracy has been achieved by using evolutionary information contained in the multiple sequence alignment. The final network yields an overall prediction accuracy of 75.5% when tested by sevenfold cross-validation on a set of 426 nonhomologous protein chains. The corresponding Q(pred), Q(obs), and Matthews correlation coefficient values are 49.8%, 72.3%, and 0.43, respectively, and are the best among all the previously published beta-turn prediction methods. The Web server BetaTPred2 (http://www.imtech.res.in/raghava/betatpred2/) has been developed based on this approach."^^ . "2003-03" . . "12" . "3" . . "Wiley"^^ . . . "Protein science : a publication of the Protein Society"^^ . . . "09618368" . . . . . . . . . . "G.P.S."^^ . "Raghava"^^ . "G.P.S. Raghava"^^ . . "Harpreet"^^ . "Kaur"^^ . "Harpreet Kaur"^^ . . . . . . "Prediction of beta-turns in proteins from multiple alignment using neural network. (PDF)"^^ . . . . . "Prediction of beta-turns in proteins from multiple alignment using neural network. (Image (PNG))"^^ . . . . . . "Prediction of beta-turns in proteins from multiple alignment using neural network. (Image (PNG))"^^ . . . . . . "Prediction of beta-turns in proteins from multiple alignment using neural network. (Image (PNG))"^^ . . . . . . "Prediction of beta-turns in proteins from multiple alignment using neural network. (Image (PNG))"^^ . . . . . . "Prediction of beta-turns in proteins from multiple alignment using neural network. (Indexer Terms)"^^ . . . . . "HTML Summary of #252 \n\nPrediction of beta-turns in proteins from multiple alignment using neural network.\n\n" . "text/html" . . . "QR Microbiology"@en . .