title: GWFASTA: server for FASTA search in eukaryotic and microbial genomes.
creator: Issac, Biju
creator: Raghava, G.P.S.
subject: QR Microbiology
description: Similarity searches are a powerful method for solving important biological problems such as database scanning, evolutionary studies, gene prediction, and protein structure prediction. FASTA is a widely used sequence comparison tool for rapid database scanning. Here we describe the GWFASTA server that was developed to assist the FASTA user in similarity searches against partially and/or completely sequenced genomes. GWFASTA consists of more than 60 microbial genomes, eight eukaryote genomes, and proteomes of annotatedgenomes. Infact, it provides the maximum number of databases for similarity searching from a single platform. GWFASTA allows the submission of more than one sequence as a single query for a FASTA search. It also provides integrated post-processing of FASTA output, including compositional analysis of proteins, multiple sequences alignment, and phylogenetic analysis. Furthermore, it summarizes the search results organism-wise for prokaryotes and chromosome-wise for eukaryotes. Thus, the integration of different tools for sequence analyses makes GWFASTA a powerful toolfor biologists.
publisher: Informa healthcare/ Biotechniques.com
date: 2002-09
type: Article
type: PeerReviewed
format: application/pdf
identifier: http://crdd.osdd.net/open/262/1/raghava2002.1.pdf
relation: http://www.biotechniques.com/multimedia/archive/00009/02333st05_9075a.pdf
identifier:   Issac, Biju and Raghava, G.P.S.  (2002) GWFASTA: server for FASTA search in eukaryotic and microbial genomes.  BioTechniques, 33 (3).  548-50, 552, 554.  ISSN 0736-6205     
relation: http://crdd.osdd.net/open/262/