creators_name: Issac, Biju
creators_name: Raghava, G.P.S.
type: article
datestamp: 2012-01-05 15:11:53
lastmod: 2012-01-05 15:11:53
metadata_visibility: show
title: GWFASTA: server for FASTA search in eukaryotic and microbial genomes.
ispublished: pub
subjects: QR
full_text_status: restricted
note: Copyright of this article belongs to Informa Healthcare.
abstract: Similarity searches are a powerful method for solving important biological problems such as database scanning, evolutionary studies, gene prediction, and protein structure prediction. FASTA is a widely used sequence comparison tool for rapid database scanning. Here we describe the GWFASTA server that was developed to assist the FASTA user in similarity searches against partially and/or completely sequenced genomes. GWFASTA consists of more than 60 microbial genomes, eight eukaryote genomes, and proteomes of annotatedgenomes. Infact, it provides the maximum number of databases for similarity searching from a single platform. GWFASTA allows the submission of more than one sequence as a single query for a FASTA search. It also provides integrated post-processing of FASTA output, including compositional analysis of proteins, multiple sequences alignment, and phylogenetic analysis. Furthermore, it summarizes the search results organism-wise for prokaryotes and chromosome-wise for eukaryotes. Thus, the integration of different tools for sequence analyses makes GWFASTA a powerful toolfor biologists.
date: 2002-09
date_type: published
publication: BioTechniques
volume: 33
number: 3
publisher: Informa healthcare/ Biotechniques.com
pagerange: 548-50, 552, 554
refereed: TRUE
issn: 0736-6205
official_url: http://www.biotechniques.com/multimedia/archive/00009/02333st05_9075a.pdf
related_url_url: http://www.biotechniques.com/multimedia/archive/00009/02333st05_9075a.pdf
related_url_type: pub
citation:   Issac, Biju and Raghava, G.P.S.  (2002) GWFASTA: server for FASTA search in eukaryotic and microbial genomes.  BioTechniques, 33 (3).  548-50, 552, 554.  ISSN 0736-6205     
document_url: http://crdd.osdd.net/open/262/1/raghava2002.1.pdf