title: Water-soluble glutathione-CdS QDs with exceptional antimicrobial properties synthesized via green route for fluorescence sensing of fluoroquinolones.
creator: Malik, Rupal
creator: Pinnaka, Anil Kumar
creator: Kaur, Manpreet
creator: Kumar, Vinod
creator: Kulbhushan, Tikko
creator: Singh, Sandeep
creator: Kaushik, Anupama
creator: Singhal, Sonal
subject: QR Microbiology
description: BACKGROUND Continual emergence of quinolones in the environment has raised concerns and the repercussions are almost unimaginable. Along with this an increase of antibiotic resistance in microbes has encouraged the pharmaceutical and food industry to create new antimicrobial agents. Nano-range materials with exceptional antimicrobial properties synthesized via green routes for fluorescence sensing of fluoroquinolones have rarely been reported. RESULTS A facile, eco-friendly and green approach was utilized for the synthesis of water soluble glutathione (GSH) functionalized CdS quantum dots (QDs) for the selective detection of fluoroquinolones. The prepared QDs exhibited a strong emission peak at 460 nm and the addition of fluoroquinolones caused enhancement and significant blue shift (similar to 50 nm) in the intensity, revealing sensitive and selective detection of fluoroquinolones. The limit of detection was found to be 2.2 mu mol L-1. Also, antimicrobial activities of the QDs were assessed against both Gram positive and Gram negative bacteria and the QDs were found to be effective against the Gram positive bacteria especially Bacillus species in comparison with the Gram negative bacteria. CONCLUSIONS The current study offers a green route to synthesize water soluble and stable QDs for sensing with exceptional antimicrobial properties. (c) 2018 Society of Chemical Industry
publisher: Wiley
date: 2019-04-09
type: Article
type: PeerReviewed
identifier:   Malik, Rupal and Pinnaka, Anil Kumar and Kaur, Manpreet and Kumar, Vinod and Kulbhushan, Tikko and Singh, Sandeep and Kaushik, Anupama and Singhal, Sonal  (2019) Water-soluble glutathione-CdS QDs with exceptional antimicrobial properties synthesized via green route for fluorescence sensing of fluoroquinolones.  Journal of Chemical Technology and Biotechnology, 94 (4).  pp. 1082-1090.  ISSN 02643421     
relation: http://crdd.osdd.net/open/2643/