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dc:title "HTML Summary of #2648 \n\nSensitivity Enhancement of Electrochemical Biosensor for Point of Care (POC) Applications: Vi Antigen Detection as a Case Study\n\n";
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bibo:abstract "A novel approach for signal enhancement of electrochemical biosensors by incorporating mechanical vibrations has been developed. We report the electrochemical study of the ferricyanide and ferrocyanide $\\left(\\,{\\left[{\\rm{Fe}}{\\left({\\rm{CN}}\\right)}_{6}\\right]}^{-3/-4}\\right)$ a redox couple, at room temperature (~25 °C), under the effect of mechanical vibrations of different frequencies applied to the sensor, for sensitivity enhancement. The experimental results showed a sensitivity enhancement of ~332% (from $3.125\\,{\\rm{nA}}\\,\\mu {{\\rm{M}}}^{-1}$ to $13.5\\,{\\rm{nA}}\\,\\mu {{\\rm{M}}}^{-1}$) at 88.75 Hz of vibration. This novel approach of signal sensitivity enhancement is also validated with antibody immobilization-based Vi antigen detection for typhoid assessment. The sensitivity enhancement up to ~15% is achieved for Vi antigen detection under the mechanical vibration of 120 Hz. The sensor is fabricated using microfabrication technology. The vibration-assisted ultrasensitive biosensing platform is also prototyped as a portable and Internet of Thing (IoT) enabled device, suitable for point-of-care applications. Detailed features of the prototype along with the test results are elaborated in the paper."^^xsd:string;
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bibo:issue "1";
bibo:status ,
;
bibo:volume "168";
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dct:date "2021-01-14";
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dct:title "Sensitivity Enhancement of Electrochemical Biosensor for Point of Care (POC) Applications: Vi Antigen Detection as a Case Study"^^xsd:string;
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skos:prefLabel "QR Microbiology"@en .
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foaf:familyName "Prajesh"^^xsd:string;
foaf:givenName "Rahul"^^xsd:string;
foaf:name "Rahul Prajesh"^^xsd:string;
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foaf:name "Journal of the Electrochemical Society"^^xsd:string;
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