@article{open279, volume = {1}, author = {Vishal Agrawal and R K Kishan}, note = {OPEN ACCESS}, title = {Functional evolution of two subtly different (similar) folds.}, publisher = {Biomedcentral}, journal = {BMC structural biology}, pages = {5}, year = {2001}, url = {http://crdd.osdd.net/open/279/}, abstract = {The function of Oligonucleotide/oligosaccharide-binding (OB) fold proteins was restricted to either DNA/RNA binding or sugar binding whereas the Src homology 3 (SH3) domain like proteins bind to a variety of ligands through loop modulations. A question was raised whether the evolution of these two folds was through DNA shuffling.} }