title: Host factors subverted by Mycobacterium tuberculosis: Potential targets for host directed therapy
creator: Kalra, Rashi
creator: Tiwari, Drishti
creator: Dkhar, H Kitdorlang
creator: Bhagyaraj, Ella
creator: Kumar, Rakesh
creator: Bhardwaj, Anshu
creator: Gupta, Pawan
subject: QR Microbiology
description: Despite new approaches in the diagnosis and treatment of tuberculosis (TB), it continues to be a major health burden. Several immunotherapies that potentiate the immune response have come up as adjuncts to drug therapies against drug resistant TB strains; however, there needs to be an urgent appraisal of host specific drug targets for improving their clinical management and to curtail disease progression. Presently, various host directed therapies (HDTs) exist (repurposed drugs, nutraceuticals, monoclonal antibodies and immunomodulatory agents), but these mostly address molecules that combat disease progression.
publisher: Informa healthcare
date: 2021-09-22
type: Article
type: PeerReviewed
relation: https://www.tandfonline.com/doi/abs/10.1080/08830185.2021.1990277?journalCode=iiri20
identifier:   Kalra, Rashi and Tiwari, Drishti and Dkhar, H Kitdorlang and Bhagyaraj, Ella and Kumar, Rakesh and Bhardwaj, Anshu and Gupta, Pawan  (2021) Host factors subverted by Mycobacterium tuberculosis: Potential targets for host directed therapy.  International reviews of immunology.   ISSN 1563-5244     
relation: http://crdd.osdd.net/open/2951/