TY  - JOUR
N1  - The copyright of this article belongs to Dove Press
ID  - open2990
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9005233/
A1  - Rana, Vibhuti 
A1  - Singh, Nittu
A1  - Nikam, Chaitali
A1  - Kambli, Priti
A1  - Singh, Pravin Kumar
A1  - Singh, Urmila
A1  - Jain, Amita
A1  - Rodrigues, Camilla 
A1  - Sharma, Charu
Y1  - 2022/04/08/
N2  - The mechanistic details of first line drug (FLD) resistance have been thoroughly explored but the genetic resistance mechanisms of second line injectables, which form the backbone of the combinatorial drug resistant tuberculosis therapy, are partially identified. This study aims to highlight the genetic and spoligotypic differences in the second line drug (SLD) resistant and sensitive Mycobacterium tuberculosis (Mtb) clinical isolates from Mumbai (Western India) and Lucknow (Northern India).
PB  - Dove Press
JF  - Infection and Drug Resistance 
VL  - 15
KW  - drug resistant tuberculosis; single nucleotide polymorphism; rrs; eis; whiB7; spoligotyping
TI  - Molecular Epidemiology and Polymorphism Analysis in Drug-Resistant Genes in M. tuberculosis Clinical Isolates from Western and Northern India
SP  - 1717
EP  - 1732
ER  -