%A Vibhuti  Rana
%A Nittu Singh
%A Chaitali Nikam
%A Priti Kambli
%A Pravin Kumar Singh
%A Urmila Singh
%A Amita Jain
%A Camilla  Rodrigues
%A Charu Sharma
%O The copyright of this article belongs to Dove Press
%J Infection and Drug Resistance 
%T Molecular Epidemiology and Polymorphism Analysis in Drug-Resistant Genes in M. tuberculosis Clinical Isolates from Western and Northern India
%X The mechanistic details of first line drug (FLD) resistance have been thoroughly explored but the genetic resistance mechanisms of second line injectables, which form the backbone of the combinatorial drug resistant tuberculosis therapy, are partially identified. This study aims to highlight the genetic and spoligotypic differences in the second line drug (SLD) resistant and sensitive Mycobacterium tuberculosis (Mtb) clinical isolates from Mumbai (Western India) and Lucknow (Northern India).
%K drug resistant tuberculosis; single nucleotide polymorphism; rrs; eis; whiB7; spoligotyping
%P 1717-1732
%V 15
%D 2022
%I Dove Press
%L open2990