creators_name: Rana, Vibhuti 
creators_name: Singh, Nittu
creators_name: Nikam, Chaitali
creators_name: Kambli, Priti
creators_name: Singh, Pravin Kumar
creators_name: Singh, Urmila
creators_name: Jain, Amita
creators_name: Rodrigues, Camilla 
creators_name: Sharma, Charu
type: article
datestamp: 2022-07-25 05:46:29
lastmod: 2022-07-25 05:46:29
metadata_visibility: show
title: Molecular Epidemiology and Polymorphism Analysis in Drug-Resistant Genes in M. tuberculosis Clinical Isolates from Western and Northern India
ispublished: pub
subjects: QR
keywords: drug resistant tuberculosis; single nucleotide polymorphism; rrs; eis; whiB7; spoligotyping
note: The copyright of this article belongs to Dove Press
abstract: The mechanistic details of first line drug (FLD) resistance have been thoroughly explored but the genetic resistance mechanisms of second line injectables, which form the backbone of the combinatorial drug resistant tuberculosis therapy, are partially identified. This study aims to highlight the genetic and spoligotypic differences in the second line drug (SLD) resistant and sensitive Mycobacterium tuberculosis (Mtb) clinical isolates from Mumbai (Western India) and Lucknow (Northern India).
date: 2022-04-08
date_type: published
publication: Infection and Drug Resistance 
volume: 15
publisher: Dove Press
pagerange: 1717-1732
refereed: TRUE
official_url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9005233/
citation:   Rana, Vibhuti  and Singh, Nittu and Nikam, Chaitali and Kambli, Priti and Singh, Pravin Kumar and Singh, Urmila and Jain, Amita and Rodrigues, Camilla  and Sharma, Charu  (2022) Molecular Epidemiology and Polymorphism Analysis in Drug-Resistant Genes in M. tuberculosis Clinical Isolates from Western and Northern India.  Infection and Drug Resistance , 15.  pp. 1717-1732.