creators_name: Garg, Harry creators_name: Ringe, Rajesh P. creators_name: Das, Supankar creators_name: Parkash , Suraj creators_name: Thakur, Bhuwaneshwar creators_name: Delipan, Rathina creators_name: Kumar, Ajay creators_name: Kulkarni, Kishore creators_name: Bansal, Kanika creators_name: Patil, Prabhu B creators_name: Alam , Tabish creators_name: Balam, Babu Nagesh creators_name: Meena, Chandan Swaroop creators_name: Thakur, Krishan Gopal creators_name: Kumar, Ashok creators_name: Kumar, Ashwani type: article datestamp: 2023-06-07 07:55:08 lastmod: 2023-06-07 07:55:08 metadata_visibility: show title: UVC-Based Air Disinfection Systems for Rapid Inactivation of SARS-CoV-2 Present in the Air. ispublished: pub subjects: QR keywords: COVID-19; SARS-CoV-2; UVC; aerosols; disinfection note: The copyright of this article belongs to MDPI AG abstract: The World Health Organization (WHO) declared in May 2021 that SARS-CoV-2 is transmitted not only by close contact with infectious respiratory fluids from infected people or contaminated materials but also indirectly through air. Airborne transmission has serious implications for the control measures we can deploy, given the emergence of more transmissible variants. This emphasizes the need to deploy a mechanism to reduce the viral load in the air, especially in closed and crowded places such as hospitals, public transport buses, etc. In this study, we explored ultraviolet C (UVC) radiation for its ability to inactivate the SARS-CoV-2 particles present in aerosols and designed an air disinfection system to eliminate infectious viruses. We studied the virus inactivation kinetics to identify the UVC dosage required to achieve maximum virus inactivation. Based on the experimental data, UVC-based devices were designed for the sanitization of air through HVAC systems in closed spaces. Further, a risk assessment model to estimate the risk reduction was applied which showed that the use of UVC radiation could result in the reduction of the risk of infection in occupied spaces by up to 90%. date: 2023-03-07 date_type: published publication: Pathogens volume: 12 number: 3 publisher: MDPI AG refereed: TRUE official_url: https://www.mdpi.com/2076-0817/12/3/419 citation: Garg, Harry and Ringe, Rajesh P. and Das, Supankar and Parkash , Suraj and Thakur, Bhuwaneshwar and Delipan, Rathina and Kumar, Ajay and Kulkarni, Kishore and Bansal, Kanika and Patil, Prabhu B and Alam , Tabish and Balam, Babu Nagesh and Meena, Chandan Swaroop and Thakur, Krishan Gopal and Kumar, Ashok and Kumar, Ashwani (2023) UVC-Based Air Disinfection Systems for Rapid Inactivation of SARS-CoV-2 Present in the Air. Pathogens, 12 (3).