@article{open3176, volume = {14}, month = {December}, author = {Ashish Kumar Dubey and Mohini Sharma and Parul . and Sachin Raut and Pawan Gupta and Neeraj Khatri}, note = {The copyright of this article belongs to Frontiers Media S.A}, title = {Healing wounds, defeating biofilms: Lactiplantibacillus plantarum in tackling MRSA infections }, publisher = {Frontiers Media S.A}, journal = {Frontiers in microbiology}, year = {2023}, keywords = {AMR; Lactoplantibacillus plantarum; MRSA; biofilm; cell-free supernatant; probiotics; wound healing}, url = {http://crdd.osdd.net/open/3176/}, abstract = {Introduction: Methicillin-resistant Staphylococcus aureus (MRSA) infections are well-known hospital-borne infections and are a major contributing factor to global health concerns of antimicrobial resistance due to the formation of biofilms. Probiotics are known to assist in the healing of wounds through immunomodulation and also possess anti-pathogen properties via competitive inhibition. The probiotic bacterium, Lactiplantibacillus plantarum MTCC 2621 and its cell-free supernatant (Lp2621) have previously been reported to have antibacterial, excellent antioxidant, and wound healing activity in in vitro conditions and wounds contaminated with S. aureus in mice.} }