TY  - JOUR
ID  - open3210
UR  - http://dx.doi.org/10.1039/D5CC02317C
A1  - Chhabra, Sonali
A1  - Parkesh, Raman
Y1  - 2025///
N2  - We introduce a dual-purpose solvatochromic naphthalimide-benzothiazinone (BTZ) conjugate with theranostic potential that enables specific and rapid detection of Mycobacterium tuberculosis by targeting the DprE1 enzyme, while also exhibiting antimicrobial activity. The photoinduced electron transfer (PeT)-based fluorophore incorporates into the mycobacterial cell wall, producing detectable fluorescence within 15 minutes and thus, highlighting its suitability for rapid, point-of-care TB detection in low-resource settings.
PB  - The Royal Society of Chemistry
JF  - Chem. Commun.
VL  - 61
TI  - A dual-function probe for inhibition and rapid detection of Mycobacterium tuberculosis
SP  - 12123
EP  - 12126
ER  -