…
comment: The repository administrator has not yet configured an RDF license.
primary topic: Eco-friendly synthesis of silver nanoparticles from Trans-Himalayan herbs

Eco-friendly synthesis of silver nanoparticles from Trans-Himalayan herbs
type: AcademicArticle
type: Article
abstract: The current study aims to synthesise silver nanoparticles (AgNPs) using three medicinal plants-Inula racemosa, Rhodiola imbricata, and Ephedra gerardiana-native to the Trans-Himalayan region. These plants were specifically selected due to their well-documented ethnomedicinal uses and rich phytochemical profiles, particularly in phenolic compounds. The study aims to harness their bioactive potential for the development of eco-friendly, cost-effective nanomaterials with therapeutic applications. Synthesised AgNPs were characterised via UV--VIS spectrophotometer, SEM, FTIR, DLS, TEM and EDX analysis. The absorption peaks at 410 nm (I. racemosa), 440 nm (R. imbricata), and 420 nm (E. gerardiana), confirming nanoparticle formation via surface plasmon resonance. Phytochemical analysis highlighted phenolics as key agents in nanoparticle reduction and capping. Although the AgNPs showed lower antioxidant activity than the crude extracts but exhibited superior antibacterial efficacy against multidrug-resistant bacterial strains, outperforming the standard antibiotic Ampicillin. Cytotoxicity evaluation against MCF-7 breast cancer cells revealed that I. racemosa root extract and its AgNPs had the highest anticancer activity, with ICâ� â�� values of 64.93 μg/mL and 55.88 μg/mL, respectively. This research proposes a sustainable approach to develop alternative antibacterial and anticancer agents, potentially addressing the rising global challenge of antibiotic resistance and cancer burden through plant-based nanotechnology.
date: 2025-10
volume: 10
issue: 4
author list: authors
type: EPrint
type: ArticleEPrint
is part of: repository

Defence Scientific Information and Documentation Centre
type: Organization

Def. Life Sci. J.
type: Collection

Raj Kumar
type: Person
given name: Raj
family name: Kumar

Priyanka Pandita
type: Person
given name: Priyanka
family name: Pandita

Om Prakash Chaurasia
type: Person
given name: Om Prakash
family name: Chaurasia

Akshay Kumar
type: Person
given name: Akshay
family name: Kumar

Mohan Singh Thakur
type: Person
given name: Mohan Singh
family name: Thakur

Shardulya Shukla
type: Person
given name: Shardulya
family name: Shukla

Souvik Manna
type: Person
given name: Souvik
family name: Manna

Manoj Kumar Patel
type: Person
given name: Manoj Kumar
family name: Patel

HTML Summary of #3250 Eco-friendly synthesis of silver nanoparticles from Trans-Himalayan herbs
format: text/html
primary topic: Eco-friendly synthesis of silver nanoparticles from Trans-Himalayan herbs