…
comment: The repository administrator has not yet configured an RDF license.
primary topic: From defense to dysfunction: Autophagy's dual role in disease pathophysiology

From defense to dysfunction: Autophagy's dual role in disease pathophysiology
type: AcademicArticle
type: Article
abstract: Autophagy is a fundamental pillar of cellular resilience, indispensable for maintaining cellular health and vitality. It coordinates the meticulous breakdown of cytoplasmic macromolecules as a guardian of cell metabolism, genomic integrity, and survival. In the complex play of biological warfare, autophagy emerges as a firm defender, bravely confronting various pathogenic, infectious, and cancerous adversaries. Nevertheless, its role transcends mere defense, wielding both protective and harmful effects in the complex landscape of disease pathogenesis. From the onslaught of infectious outbreaks to the devious progression of chronic lifestyle disorders, autophagy emerges as a central protagonist, convolutedly shaping the trajectory of cellular health and disease progression. In this article, we embark on a journey into the complicated web of molecular and immunological mechanisms that govern autophagy's profound influence over disease. Our focus sharpens on dissecting the impact of various autophagy-associated proteins on the kaleidoscope of immune responses, spanning the spectrum from infectious outbreaks to chronic lifestyle ailments. Through this voyage of discovery, we unveil the vast potential of autophagy as a therapeutic linchpin, offering tantalizing prospects for targeted interventions and innovative treatment modalities that promise to transform the landscape of disease management.
date: 2024-10
volume: 981
author list: authors
type: EPrint
type: ArticleEPrint
is part of: repository

European Journal of Pharmacology
type: Collection

Jonaid Ahmad Malik
type: Person
given name: Jonaid Ahmad
family name: Malik

Javed N Agrewala
type: Person
given name: Javed N
family name: Agrewala

Deepjyoti Kumar Das
type: Person
given name: Deepjyoti Kumar
family name: Das

Sanpreet Singh
type: Person
given name: Sanpreet
family name: Singh

Sidhanta Nanda
type: Person
given name: Sidhanta
family name: Nanda

Mohammad Adeel Zafar
type: Person
given name: Mohammad Adeel
family name: Zafar

Taruna Lamba
type: Person
given name: Taruna
family name: Lamba

Hilal Bashir
type: Person
given name: Hilal
family name: Bashir

Mohammad Affan Khan
type: Person
given name: Mohammad Affan
family name: Khan

Gurpreet Kaur
type: Person
given name: Gurpreet
family name: Kaur

HTML Summary of #3327 From defense to dysfunction: Autophagy's dual role in disease pathophysiology
format: text/html
primary topic: From defense to dysfunction: Autophagy's dual role in disease pathophysiology