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primary topic: Role of natural killer and B cell interaction in inducing pathogen specific immune responses

Role of natural killer and B cell interaction in inducing pathogen specific immune responses
type: AcademicArticle
type: Article
abstract: The innate lymphoid cell (ILC) system comprising of the circulating and tissue-resident cells is known to clear infectious pathogens, establish immune homeostasis as well as confer antitumor immunity. Human natural killer cells (hNKs) and other ILCs carry out mopping of the infectious pathogens and perform cytolytic activity regulated by the non-adaptive immune system. The NK cells generate immunological memory and rapid recall response tightly regulated by the adaptive immunity. The interaction of NK and B cell, and its role to induce the pathogen specific immunity is not fully understood. Hence, present article sheds light on the interaction between NK and B cells and resulting immune responses in the infectious diseases. The immune responses elicited by the NK-B cell interaction is of particular importance for developing therapeutic vaccines against the infectious pathogens. Further, experimental evidences suggest the immune-response driven by NK cell population elicits the host-specific antibodies and memory B cells. Also, recently developed humanized immune system (HIS) mice and their importance in to understanding the NK-B cell interaction and resulting pathogen specific immunity has been discussed.
date: 2023-02-02
volume: 42
issue: 4
status: peerReviewed
status: published
author list: authors
type: EPrint
type: ArticleEPrint
is part of: repository
subject: QR Microbiology

Informa UK Limited
type: Organization

Int. Rev. Immunol.
type: Collection

Sushmita Negi
type: Person
given name: Sushmita
family name: Negi

Rajeev K Tyagi
type: Person
given name: Rajeev K
family name: Tyagi

Sarat K Dalai
type: Person
given name: Sarat K
family name: Dalai

Nikunj Tandel
type: Person
given name: Nikunj
family name: Tandel

HTML Summary of #3405 Role of natural killer and B cell interaction in inducing pathogen specific immune responses
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primary topic: Role of natural killer and B cell interaction in inducing pathogen specific immune responses

QR Microbiology
type: Concept