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primary topic: Genomic and functional insights into aromatic compound degradation by Delftia strain PS-11 isolated from freshwater pufferfish

Genomic and functional insights into aromatic compound degradation by Delftia strain PS-11 isolated from freshwater pufferfish
type: AcademicArticle
type: Article
abstract: This study describes the functional genomic features and aromatic compound degradation potential of Delftia strain PS-11, isolated from the skin mucus of a freshwater pufferfish (Tetraodon cutcutia). Whole-genome sequence analysis of strain PS-11 revealed genetic attributes associated with species distinctiveness. The overall genome-relatedness indices, such as in silico DNA-DNA hybridization, are below 70%, and average nucleotide identity and average amino acid identity were below the threshold value, that is, 95% to 96%, respectively. Phylogenomic analysis based on genome-wide core genes showed that strain PS-11 clustered with Delftia acidovorans NBRC 14950T. Furthermore, genome analysis identified multiple gene clusters involved in the degradation of aromatic compounds, including phenol, benzoic acid, and hydroxybenzoic acid. We determined the specific activities of key metabolic enzymes in cell-free extracts, including catechol-1,2-dioxygenase, catechol-2,3-dioxygenase, protocatechuic acid 4,5-dioxygenase, and gentisate 1,2-dioxygenase. To our knowledge, the presence of Delftia strains associated with pufferfish has not been reported previously. These findings suggest that members of this genus occupy a broader and more diverse range of ecological habitats than previously recognized and may play a potential role in the remediation of aromatic pollutants.IMPORTANCEDelftia strain PS-11 described in this study associated with freshwater pufferfish skin is capable of degrading aromatic compounds. Gene clusters in the form of operons involved in degradation of phenol, benzoic acid, and hydroxybenzoic acid were present. Enzymatic studies support the proposed degradation pathways. Our study suggests that the presence of xenobiotics-degrading Delftia strain in the skin of pufferfish adds a new ecological niche to this bacteria. The observed metabolic pathway in the degradation of aromatic compounds indicates niche-specific adaptive evolution for this bacterium.
date: 2026-04-01
volume: 14
issue: 5
status: peerReviewed
status: published
author list: authors
type: EPrint
type: ArticleEPrint
is part of: repository
has document: Genomic and functional insights into aromatic compound degradation by Delftia strain PS-11 isolated from freshwater pufferfish (HTML)
subject: QR Microbiology

Genomic and functional insights into aromatic compound degradation by Delftia strain PS-11 isolated from freshwater pufferfish (HTML)
type: Document
has file: references (7).bib
has part: references (7).bib

American Society for Microbiology
type: Organization

Microbiol. Spectr.
type: Collection

Prashant S Phale
type: Person
given name: Prashant S
family name: Phale

Sandesh Papade
type: Person
given name: Sandesh
family name: Papade

Subrata K Das
type: Person
given name: Subrata K
family name: Das

Tanmoy Debnath
type: Person
given name: Tanmoy
family name: Debnath

Sushanta Deb
type: Person
given name: Sushanta
family name: Deb

Ritu Rani Archana Kujur
type: Person
given name: Ritu Rani
family name: Archana Kujur

HTML Summary of #3477 Genomic and functional insights into aromatic compound degradation by Delftia strain PS-11 isolated from freshwater pufferfish
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primary topic: Genomic and functional insights into aromatic compound degradation by Delftia strain PS-11 isolated from freshwater pufferfish

QR Microbiology
type: Concept