<> "The repository administrator has not yet configured an RDF license."^^ . <> . . . "A 38-kDa antigen of Mycobacterium tuberculosis predominantly induces the secretion of interleukin-2, interferon-gamma and IgG2a antibodies."^^ . "In the present study, mice of 3 different haplotypes (H-2d, H-2k and H-2b) were sensitized subcutaneously with heat-killed H37Ra or 38-kDa antigen of Mycobacterium tuberculosis. Lymphocytes obtained from immunized animals were challenged in vitro with 38-kDa antigen in both cases. The dominant pattern of Th1-like lymphokines (IL-2 and IFN-gamma) and preferential production of 38-kDa specific IgG2a-type antibody were observed. It was noted that 38-kDa antigen was recognized permissively by all 3 strains of mice used in the present study. It was interesting to note that C3H/HeJ mice, which express BCG-resistant alleles showed a higher level of proliferative as well as cytokine response as compared to BALB/c and C57BL/6 mice, which bear BCG-susceptible alleles. These results suggest that not only in recall responses but also during the induction as well as expression phase of the immune response mediated by 38-kDa antigen of M. tuberculosis the Th1-like immune response predominates."^^ . "1995" . "39" . "10" . . "Center for Academic Publications Japan"^^ . . . "Microbiology and immunology"^^ . . . "03855600" . . . . . . . . . . "J N"^^ . "Agrewala"^^ . "J N Agrewala"^^ . . "G C"^^ . "Mishra"^^ . "G C Mishra"^^ . . . . . "HTML Summary of #398 \n\nA 38-kDa antigen of Mycobacterium tuberculosis predominantly induces the secretion of interleukin-2, interferon-gamma and IgG2a antibodies.\n\n" . "text/html" . . . "QR Microbiology"@en . .