creators_name: Banerjee, U C
type: article
datestamp: 2011-12-12 15:36:27
lastmod: 2014-03-28 10:51:28
metadata_visibility: show
title: Transformation of rifamycin B with growing and resting cells of Curvularia lunata.
ispublished: pub
subjects: QR
full_text_status: none
note: Copyright of this article belongs to Elsevier Science
abstract: Growing and resting cell systems of Curvularia lunata were used for the transformation of rifamycin B to rifamycin S. In the case of growing cells, rifamycin B was added at the time of inoculation and at the different phases of growth. Interestingly, it was found that C. lunata could grow in the presence of rifamycin B and could convert rifamycin B to rifamycin S. Growing cells 24 and 48 h of age were capable of transforming rifamycin B. Resting cells, cultivated at the exponential or early stationary phase, were found to be very active, and the resting cells of different ages were repeatedly used for the transformation reaction. Growing cells of 72 and 96 h were not capable of transforming rifamycin B, whereas resting cells of similar ages were very active. Due to the adsorption of rifamycins by the growing and resting cells of C. lunata, the stoichiometric yield of rifamycin S was not obtained.
date: 1993-12
date_type: published
publication: Enzyme and microbial technology
volume: 15
number: 12
publisher: Elsevier Science
pagerange: 1037-41
refereed: TRUE
issn: 0141-0229
citation:   Banerjee, U C  (1993) Transformation of rifamycin B with growing and resting cells of Curvularia lunata.  Enzyme and microbial technology, 15 (12).  pp. 1037-41.  ISSN 0141-0229     
document_url: http://crdd.osdd.net/open/414/1/banerjee1993.pdf