@article{open570, volume = {10}, author = {Manish Kumar and G.P.S. Raghava}, note = {Open Access}, title = {Prediction of nuclear proteins using SVM and HMM models.}, publisher = {BIomedcentral}, journal = {BMC bioinformatics}, pages = {22}, year = {2009}, url = {http://crdd.osdd.net/open/570/}, abstract = {This study describes a highly accurate method for predicting nuclear proteins. SVM module has been developed for the first time using SAAC for predicting nuclear proteins, where amino acid composition of N-terminus and the remaining protein were computed separately. In addition, our study is a first documentation where exclusively nuclear and non-nuclear domains have been identified and used for predicting nuclear proteins. The performance of the method improved further by combining both approaches together.} }