%0 Journal Article %@ 1471-2105 %A Kumar, Manish %A Raghava, G.P.S. %D 2009 %F open:570 %I BIomedcentral %J BMC bioinformatics %P 22 %T Prediction of nuclear proteins using SVM and HMM models. %U http://crdd.osdd.net/open/570/ %V 10 %X This study describes a highly accurate method for predicting nuclear proteins. SVM module has been developed for the first time using SAAC for predicting nuclear proteins, where amino acid composition of N-terminus and the remaining protein were computed separately. In addition, our study is a first documentation where exclusively nuclear and non-nuclear domains have been identified and used for predicting nuclear proteins. The performance of the method improved further by combining both approaches together. %Z Open Access