%A Manish Kumar %A G.P.S. Raghava %O Open Access %J BMC bioinformatics %T Prediction of nuclear proteins using SVM and HMM models. %X This study describes a highly accurate method for predicting nuclear proteins. SVM module has been developed for the first time using SAAC for predicting nuclear proteins, where amino acid composition of N-terminus and the remaining protein were computed separately. In addition, our study is a first documentation where exclusively nuclear and non-nuclear domains have been identified and used for predicting nuclear proteins. The performance of the method improved further by combining both approaches together. %P 22 %V 10 %D 2009 %I BIomedcentral %L open570