@article{open641, volume = {388}, number = {2}, month = {July}, author = {B Bhattacharya and C Mandal and S Basu and P K Sarkar}, note = {Copyright of this articl;e belongs to Elsevier Science.}, title = {Regulation of alpha- and beta-tubulin mRNAs in rat brain during synaptogenesis.}, publisher = {Elsevier Science}, year = {1987}, journal = {Brain research}, pages = {159--62}, url = {http://crdd.osdd.net/open/641/}, abstract = {Developmental alterations in alpha- and beta-tubulin mRNA in polysomes from brains of -3 days (fetal) to 30-day-old rats were quantitated by using well-characterized chicken alpha- and beta-tubulin cDNA probes, pT1 and pT2 having 80-90\% homology with rat sequences. Northern blot analysis revealed a single major (greater than 95\%) 1.8 kb mRNA for both alpha- and beta-tubulin. Quantitation by slot hybridization indicates a virtually coordinate expression of alpha- and beta-tubulin mRNA with a maximal level around day 5 after birth, which represents the mid-phase of synaptogenesis.} }