@article{open667, volume = {6}, number = {1}, author = {P R Patnaik}, note = {Copyright of this article belongs to Springer Science.}, title = {Sensitivity analysis of fed-batch fermentation for the production of penicillin G}, publisher = {Springer Science}, year = {1992}, journal = {Biotechnology Techniques}, pages = {9--14}, url = {http://crdd.osdd.net/open/667/}, abstract = {The mixed metabolism model of Nicolaiet al. (1991) has been used to analyse the sensitivity of fed-batch fermentation for penicillin G with respect to four parameters. The cases of fully endogenous, fully maintenance and mixed metabolisms have been studied. Sensitivities with respect to two parameters,K x andK i, were much larger than for the other two. Differences between the three kinds of metabolism were sharpest forK p. The implications of both observations are discussed. } }