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primary topic: Quantification of the variation in percentage identity for protein sequence alignments.

Quantification of the variation in percentage identity for protein sequence alignments.
type: AcademicArticle
type: Article
abstract: Although it is well known amongst expert sequence analysts that PID is a poor score for discriminating between protein sequences, the apparent simplicity of the percentage identity score encourages its widespread use in establishing cutoffs for structural similarity. This paper illustrates that not only is PID a poor measure of sequence similarity when compared to the Z-score, but that there is also a large uncertainty in reported PID values. Since better alternatives to PID exist to quantify sequence similarity, these should be quoted where possible in preference to PID. The findings presented here should prove helpful to those new to sequence analysis, and in warning those who seek to interpret the value of a PID reported in the literature.
date: 2006
volume: 7
is part of: BMC bioinformatics
status: peerReviewed
status: published
author list: authors
type: EPrint
type: ArticleEPrint
is part of: repository
has document: Quantification of the variation in percentage identity for protein sequence alignments. (PDF)
has version: Quantification of the variation in percentage identity for protein sequence alignments. (PDF)
has published: Quantification of the variation in percentage identity for protein sequence alignments. (PDF)
has document: Quantification of the variation in percentage identity for protein sequence alignments. (Image (PNG))
has document: Quantification of the variation in percentage identity for protein sequence alignments. (Indexer Terms)
subject: QR Microbiology

Quantification of the variation in percentage identity for protein sequence alignments. (PDF)
type: Document
license: http://creativecommons.org/licenses/by/3.0/
has file: raghava2006.4.pdf
has part: raghava2006.4.pdf

Biomedcentral
type: Organization

BMC bioinformatics
type: Collection
issn: 14712105

G.P.S. Raghava
type: Person
given name: G.P.S.
family name: Raghava

Geoffrey J Barton
type: Person
given name: Geoffrey J
family name: Barton

Quantification of the variation in percentage identity for protein sequence alignments. (Image (PNG))
type: Document
is version of: Quantification of the variation in percentage identity for protein sequence alignments. (PDF)
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Quantification of the variation in percentage identity for protein sequence alignments. (Image (PNG))
type: Document
is version of: Quantification of the variation in percentage identity for protein sequence alignments. (PDF)
is volatile version of: Quantification of the variation in percentage identity for protein sequence alignments. (PDF)
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Quantification of the variation in percentage identity for protein sequence alignments. (Image (PNG))
type: Document
is version of: Quantification of the variation in percentage identity for protein sequence alignments. (PDF)
is volatile version of: Quantification of the variation in percentage identity for protein sequence alignments. (PDF)
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Quantification of the variation in percentage identity for protein sequence alignments. (Image (PNG))
type: Document
is version of: Quantification of the variation in percentage identity for protein sequence alignments. (PDF)
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Quantification of the variation in percentage identity for protein sequence alignments. (Indexer Terms)
type: Document
is version of: Quantification of the variation in percentage identity for protein sequence alignments. (PDF)
is volatile version of: Quantification of the variation in percentage identity for protein sequence alignments. (PDF)
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primary topic: Quantification of the variation in percentage identity for protein sequence alignments.

QR Microbiology
type: Concept