TY  - JOUR
ID  - open679
UR  - http://dx.doi.org/10.1080/00986449308936200
IS  - 1
A1  - PATNAIK, P.R.
N2  - A general model is presented for recombinant fermentation in a chemostat in which micromixing may be imperfect. Using the production of tryptophan synthetase as an example and the dilution rate, D, as the bifurcation parameter, conditions are first derived for Hopf bifurcation in a perfectly mixed chemostat. The bifurcation surfaces in three-dimensional space are such that oscillatory solutions exist above the surfaces and washout conditions below. A similar analysis is done for imperfect mixing. The bifurcation region is a concave hyperboloid in the [D,f, n]-space, where f and n ; are model parameters. It is argued that poor macromixing reduces the range of D over which bifurcation to periodic solutions is possible.
VL  - 125
TI  - The Effect Of Macromixing On Oscillatory Behavior In Recombinant Fermentation In A Continuous Stirred Tank Reactor.
AV  - none
EP  - 169
N1  - Copyright of this article belongs to Taylor & Francis.
Y1  - 1993///
PB  - Taylor and francis group
JF  - Chemical Engineering Communications
KW  - Macromixing
KW  -  Recombinant
KW  -  Fermentation
KW  -  CSTR
SN  - 0098-6445
SP  - 155
ER  -