%0 Journal Article
%A Patnaik, P R
%D 1996
%F open:743
%I SAUS
%J Hungarian Journal of Industrial Chemistry
%P 193-197
%T On the role of reactive diffusion and pellet shape in the conversion of rifamycin B to rifamycin S by immobilised rifamycin oxidase.
%U http://crdd.osdd.net/open/743/
%V 24
%X The steady state performance of a well-mixed continuous flow bioreactor has been analysed for the conversion of rifamycin B to rifamycin S by rifamycin oxidase immobilised inside porous pellets. Substrate inhibition kinetics, established in a previous study, have been used and a one-point collocation employed for the concentration profiles in the pellets. The effectiveness factor, h, and the fractional conversion, X, of rifamycin B for rectangular, cylindrical and spherical pellets pass through peaks as the Thiele modulus is varied. The maxima for both η and X are highest and occur at the smallest Thiele modulus for a rectangular slab whereas a sphere is at the other extreme.