@article{open765, volume = {25}, number = {4}, title = {Principal component analysis of the effect of in-flow disturbances on recombinant beta-gaglactosidase fermentation}, author = {P R Patnaik}, year = {1997}, pages = {261--264}, journal = {Hungarian Journal of Industrial Chemistry}, keywords = {ESCHERICHIA-COLI; NEURAL-NETWORK; MICROORGANISMS; BIOREACTOR; CULTURE }, url = {http://crdd.osdd.net/open/765/}, abstract = {Principal component analysis (PCA) has been applied to the fed-batch fermentative production of recombinant beta-galactosidase to analyse the effect of inflow disturbances. Although the full model has nine time-dependent variables, PCA shows that five are sufficient to provide a good description of bioreactor dynamics for bath smooth and disturbed operations. The variables identified are physically plausible, and the reduced model predicts the original data with 95 \% accuracy.} }