TY - JOUR N1 - Copyright of this article belongs to ASM. ID - open775 UR - http://jcm.asm.org/content/36/7/2149.abstract IS - 7 A1 - Mukhopadhyay, A K A1 - Basu, A A1 - Garg, P. A1 - Ghosh, A A1 - Bhattacharya, S K A1 - Takeda, Y A1 - Nair, G B Y1 - 1998/07// N2 - We report the prevalence of the O139 serogroup in Calcutta, India, after its reemergence in August 1996 and the spread of the reemerged clone to other parts of the country by using previously established molecular markers. Phenotypically, the reemerged Vibrio cholerae O139 displayed a difference compared to those that appeared in late 1992 and 1993 in that the current O139 strains are sensitive to co-trimoxazole. Ribotyping with the enzymeBglI produced two rRNA restriction patterns in the O139 strains isolated after August 1996, and these patterns were identical to those exhibited by strains of O139 isolated in 1992. Three clones ofV. cholerae O139 are currently prevailing in the country, with strains exhibiting three bands after HindIII digestion and hybridization with a ctxA probe being dominant. The reemergence of V. cholerae O139 in Calcutta after a 32-month quiescent period reestablishes the O139 serogroup as an entity which is likely to play a crucial role in the temporal antigenic variations among the serogroups of V. cholerae causing cholera. PB - ASM JF - Journal of clinical microbiology VL - 36 SN - 0095-1137 TI - Molecular epidemiology of the re-emerged Vibrio cholerae 0139 Bengal in India SP - 2143 AV - restricted EP - 2152 ER -