%A P R Patnaik
%O Copyright of this article belongs to Springer Science.
%J Biotechnology Techniques
%T Coupling of a neural filter and a neural controller for improve-ment of fermentation performance
%X The noise associated with fermentation processes is normally minimised by a filtering technique. However, sometimes
the noise may be beneficial if it is properly regulated. For recombinant ?-galactosidase production in a
fed-batch fermentation subject to Gaussian disturbances, it is shown that a neural network trained to act as a noise
filter can allow disturbances of only a particular variance which maximizes ?-galactosidase synthesis. By coupling
such a filter with a neural controller, the productivity may be enhanced beyond what is possible with static filtering and either proportional-integral-derivative or neural control.
%N 11
%K fermentation noise, ?-galactosidase, neural control, neural filter
%P 735-738
%V 13
%D 1999
%I http://www.springerlink.com/content/v03u6m3471339374/
%R doi:10.1023/A:1008948900705
%L open813