title: Crystallographic characterisation of novel β-turn like folds in a model peptide: stabilisation by main-chain to side-chain interactions
creator: Thakur, A K
creator: Kishore, Raghuvansh
subject: QD Chemistry
description: X-Ray diffraction analysis of the model peptide Boc-Thr-Thr-OCH3 reveals the existence of distinctive conformational characteristics: semi-extended (φ=−62.1°; ψ=137.1°) and semi-folded (φ=−130.3°; ψT=5.7°) of the N- and C-terminus Thr residues, respectively. Surprisingly, an overall significantly ‘flat’ conformation is stabilised by a number of novel main-chain to side-chain intramolecular hydrogen bonds, i.e. two non-conventional: Cγi+1H⋯OCi−1 and CγiH⋯Oi+1 types and two conventional: NiH⋯Oγi and OγiH⋯Ni types of interactions
publisher: Elsevier Science
date: 2001
type: Article
type: PeerReviewed
format: application/pdf
identifier: http://crdd.osdd.net/open/863/1/kishore2001.pdf
relation: http://dx.doi.org/10.1016/S0040-4039(01)00788-2
identifier:   Thakur, A K and Kishore, Raghuvansh  (2001) Crystallographic characterisation of novel β-turn like folds in a model peptide: stabilisation by main-chain to side-chain interactions.  Tetrahedron Letters, 42 (28).  pp. 4691-4694.  ISSN 00404039     
relation: http://crdd.osdd.net/open/863/