title: Structural characterization and artificial fiber formation of Bombyx mori silk fibroin in hexafluoro-iso-propanol solvent system.
creator: Zhao, Chenhua
creator: Yao, Juming
creator: Masuda, Hiromi
creator: Kishore, Raghuvansh
creator: Asakura, Tetsuo
subject: QD Chemistry
description: High-resolution solution (13)C-NMR and CD studies of Bombyx mori silk fibroin revealed the presence of an ordered secondary structure 3(10)-helix, in hexafluoro-iso-propanol (HFIP). The solid-state structure of the silk fibroin film prepared by drying it gently from the HFIP solution still keep the structure, 3(10)-helix, which was studied with high-resolution solid state (13)C-NMR. The structural transition from the 3(10)-helix to silk II structure, heterogeneous structure including antiparallel beta-sheet, occurred during the artificial spinning from the HFIP solution. The wide-angle x-ray diffraction and differential scanning calorimetry thermograms of the artificial spinning fiber after postspinning treatments were observed together with the stress-strain curves. The results emphasize that the molecular structures, controlled morphology, and mechanical properties of the protein-based synthetic polymers can be modulated for enhancing biocompatibility.
publisher: wiley
date: 2003-06
type: Article
type: PeerReviewed
format: application/pdf
identifier: http://crdd.osdd.net/open/937/1/kishore2003.1.pdf
relation: http://onlinelibrary.wiley.com/doi/10.1002/bip.10350/pdf
identifier:   Zhao, Chenhua and Yao, Juming and Masuda, Hiromi and Kishore, Raghuvansh and Asakura, Tetsuo  (2003) Structural characterization and artificial fiber formation of Bombyx mori silk fibroin in hexafluoro-iso-propanol solvent system.  Biopolymers, 69 (2).  pp. 253-9.  ISSN 0006-3525     
relation: http://crdd.osdd.net/open/937/