creators_name: Singh, Om V creators_name: Jain, R K creators_name: Singh, Rajesh P type: article datestamp: 2012-02-14 10:31:47 lastmod: 2012-04-03 06:58:23 metadata_visibility: show title: Gluconic acid production under varying fermentation conditions byAspergillus niger ispublished: pub subjects: TP full_text_status: restricted keywords: Aspergillus niger; gluconic acid; submerged fermentation; semisolid-state fermentation; surface fermentation; solid-state surface fermentation note: Copyright of this article belongs to Wiley. abstract: The production of gluconic acid with respect to varying substrate concentrations in submerged (SmF), semisolid-state (SmSF), surface (SF), and solid-state surface (SSF) fermentations was analyzed. Under the various fermentation conditions the biomass and specific growth rate varied with different concentrations of glucose. The highest level of gluconic acid (106.5g dm�3) with 94.7% yield was obtained under SSF conditions. In all cases the maximumdegree of gluconic acid conversion was observed at on initial substrate concentration of 120g dm�3. The rate of glucose uptake increased on increasing the initial glucose concentration and glucose utilization was observed to be highest (89–94%) in the SmSF process and was comparable with the SSF and SF processes. The maximumrate of cell growth was obtained in all processes at an initial glucose concentration of 120g dm�3. The gluconic acid production and change in pH were analyzed at varying time intervals and it was observed that the SmF and SmSF processes were completed within 6 days of incubation whereas the highest yield was observed after 12 days of incubation and continued thereafter in the SSF process. # 2003 Society of Chemical Industry date: 2003 date_type: published publication: Journal of Chemical Technology & Biotechnology volume: 78 number: 2-3 publisher: http://onlinelibrary.wiley.com/doi/10.1002/jctb.748/pdf pagerange: 208-212 id_number: doi:10.1002/jctb.748 refereed: TRUE issn: 0268-2575 official_url: http://dx.doi.org/10.1002/jctb.748 related_url_url: http://onlinelibrary.wiley.com/doi/10.1002/jctb.748/pdf related_url_type: pub citation: Singh, Om V and Jain, R K and Singh, Rajesh P (2003) Gluconic acid production under varying fermentation conditions byAspergillus niger. Journal of Chemical Technology & Biotechnology, 78 (2-3). pp. 208-212. ISSN 0268-2575 document_url: http://crdd.osdd.net/open/938/1/jain2003.pdf