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primary topic: Concentration of a potent calcium oxalate monohydrate crystal growth inhibitor in the urine of normal persons and kidney stone patients by ELISA-based assay system employing monoclonal antibodies.

Concentration of a potent calcium oxalate monohydrate crystal growth inhibitor in the urine of normal persons and kidney stone patients by ELISA-based assay system employing monoclonal antibodies.
type: AcademicArticle
type: Article
abstract: Standardized calcium oxalate monohydrate (COM) crystal growth assay system was employed to study the ability of various test samples to influence growth rates of COM crystals. The inhibitory activity (IA) of various samples was expressed in terms of inhibitory units. Urine samples obtained from normal persons and kidney stone patients were found to have IA of 3.18 +/- 0.62 and 1.02 +/- 0.08, respectively. A potent inhibitor having molecular weight between 14.2 and 16.2 kDa was found to be primarily responsible for the differences observed in the urinary IAs between normal persons and kidney stone patients. The potent inhibitor was found to be tightly associated with a chromophore resembling Urobilirubin. An ELISA based assay system, using monoclonal antibodies against the above most potent inhibitor confirmed the difference observed in the urinary IA between the normal persons and kidney stone patients. This assay system has the potential to be routinely used to screen human beings for potential stone formers.
date: 2003-12-15
volume: 90
issue: 6
is part of: Journal of cellular biochemistry
status: peerReviewed
status: published
author list: authors
type: EPrint
type: ArticleEPrint
is part of: repository
has document: http://crdd.osdd.net/open/id/document/3630
has version: http://crdd.osdd.net/open/id/document/3630
has published: http://crdd.osdd.net/open/id/document/3630
has document: http://crdd.osdd.net/open/id/document/3645
has document: http://crdd.osdd.net/open/id/document/3646
has document: http://crdd.osdd.net/open/id/document/3647
has document: http://crdd.osdd.net/open/id/document/3648
has document: http://crdd.osdd.net/open/id/document/3649
subject: QR Microbiology

http://crdd.osdd.net/open/id/document/3630
type: Document
label: Concentration of a potent calcium oxalate monohydrate crystal growth inhibitor in the urine of normal persons and kidney stone patients by ELISA-based assay system employing monoclonal antibodies. (PDF)

wiley
type: Organization

Journal of cellular biochemistry
type: Collection
issn: 07302312

Mehdi F Moghadam
type: Person
given name: Mehdi F
family name: Moghadam

C Tandon
type: Person
given name: C
family name: Tandon

Grish C Varshney
type: Person
given name: Grish C
family name: Varshney

S K Sharma
type: Person
given name: S K
family name: Sharma

S K Singla
type: Person
given name: S K
family name: Singla

S K Singh
type: Person
given name: S K
family name: Singh

S Aggarwal
type: Person
given name: S
family name: Aggarwal

R K Jethi
type: Person
given name: R K
family name: Jethi

http://crdd.osdd.net/open/id/document/3645
type: Document
label: Concentration of a potent calcium oxalate monohydrate crystal growth inhibitor in the urine of normal persons and kidney stone patients by ELISA-based assay system employing monoclonal antibodies. (Indexer Terms)
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http://crdd.osdd.net/open/id/document/3646
type: Document
label: Concentration of a potent calcium oxalate monohydrate crystal growth inhibitor in the urine of normal persons and kidney stone patients by ELISA-based assay system employing monoclonal antibodies. (Image (PNG))
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http://crdd.osdd.net/open/id/document/3647
type: Document
label: Concentration of a potent calcium oxalate monohydrate crystal growth inhibitor in the urine of normal persons and kidney stone patients by ELISA-based assay system employing monoclonal antibodies. (Image (PNG))
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http://crdd.osdd.net/open/id/document/3648
type: Document
label: Concentration of a potent calcium oxalate monohydrate crystal growth inhibitor in the urine of normal persons and kidney stone patients by ELISA-based assay system employing monoclonal antibodies. (Image (PNG))
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http://crdd.osdd.net/open/id/document/3649
type: Document
label: Concentration of a potent calcium oxalate monohydrate crystal growth inhibitor in the urine of normal persons and kidney stone patients by ELISA-based assay system employing monoclonal antibodies. (Image (PNG))
is version of: http://crdd.osdd.net/open/id/document/3630
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http://crdd.osdd.net/open/939/
title: HTML Summary of #939 Concentration of a potent calcium oxalate monohydrate crystal growth inhibitor in the urine of normal persons and kidney stone patients by ELISA-based assay system employing monoclonal antibodies.
format: text/html
primary topic: Concentration of a potent calcium oxalate monohydrate crystal growth inhibitor in the urine of normal persons and kidney stone patients by ELISA-based assay system employing monoclonal antibodies.

QR Microbiology
type: Concept