creators_name: Saha, Sudipto
creators_name: Bhasin, Manoj
creators_name: Raghava, G.P.S.
type: article
datestamp: 2012-02-15 14:39:38
lastmod: 2012-02-15 14:39:38
metadata_visibility: show
title: BCIpep: A database of B-cell epitopes.
ispublished: pub
subjects: QR180
full_text_status: none
note: OPEN ACCESS
abstract: B-cell epitopes are vital in designing peptide-based vaccine, in diseases diagnosis and also for allergy research. This practical importance creates a need for an integrated source of information about them. We developed a databaseBcipep, of experimentally determined B-cell epitopes of antigenic proteins. This is a curated database where detailed information about the epitopes are collected and compiled from published literature and existing databases. It covers a wide range of pathogenic organisms like virus, bacteria, protozoa and fungi. Each entry in database provides full information about a B-cell epitope that includes amino acid sequences, source of the antigenic protein, immunogenicity, model organism and antibody generation/neutralization test. The database have number of web tools and user friendly web interface which allows user to perform various tasks; i) keyword search on any field; ii) mapping of known peptides (B-cell epitope) on a given antigen sequence; iii) BLAST search etc. It also provides links to various databases such as GenBank, PDB, SWISS-PROT and MHCBN for further detailed information about epitopes. The database now contains 2700 entries including 1350 epitopes in the non-redundant datasets
date: 2005
date_type: published
publication: Nucleic acids research
publisher: Oxford University Press
refereed: TRUE
issn: 1362-4962
official_url: http://www.oxfordjournals.org/nar/database/summary/642
related_url_url: http://www.imtech.res.in/raghava/bcipep/ 
related_url_type: author
citation:   Saha, Sudipto and Bhasin, Manoj and Raghava, G.P.S.  (2005) BCIpep: A database of B-cell epitopes.  Nucleic acids research.   ISSN 1362-4962