ntEGFR: A webserver to predict EGFR inhibitors
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Inhibitor Prediction

  KiDoQ (Mtb target)

  GDoQ (Mtb target)

  ABMpred (Mtb target)

  eBooster (Mtb target)

  MDRIpred (Mtb cell)

  CancerIN (Cancer)

  ntEGFR (Cancer EGFR)

  EGFRpred (Cancer EGFR)

  DiPCell (Pancreatic Cancer)

  DMKPred (Human Kinases)

  TLR4HI (Human TLR4)

  HIVFin (HIV)

Antigenic Properties

  Carbotope
ADMET Properties

  MetaPred (Cytochrome P450)

  ToxiPred (Aqueous toxicity)

  DrugMint (Drug-like)

  QED (Oral drug-like)
Descriptors

  Format Conversion

  WebCDK

  MetaServer
     

Generation of Chemical Analogs

ntEGFR server allow to users to design analogs of a chemical strucuture using SmiLib program. These analogs were then predicted for their inhibition activity against wild and/or mutant EGFR. For this you should submit following three basic sub-structures:
1. Structure of Scaffold.
2. Structure of Building Blocks.
3.Structure of Linkers.

Examples for scaffold, building block and linker have been provided to assist user. These examples can be used by simply clicking on the provided links.
For more information click help.
Paste Scaffold structure:
Paste Building Blocks structure:
Paste linkers :
Email Address (Optional):

Select method: EGFRwild (against wild EGFR)   EGFRmutant (against mutant EGFR)   EGFRhybrid