1P83 Chaperone date May 06, 2003
title Nmr Structure Of 1-25 Fragment Of Mycobacterium Tuberculosis Cpn10
authors A.Ciutti, O.Spiga, E.Giannozzi, M.Scarselli, D.Di Maro, D.Calamandrei, N.Niccolai, A.Bernini
compound source
Molecule: 10 Kda Chaperonin
Chain: A
Fragment: N-Terminal Domain, Residue 1-25
Synonym: Protein Cpn10, Groes Protein, Bcg-A Heat Shock Protein, 10 Kda Antigen;
Engineered: Yes
 Synthetic: Yes
Other_details: Solid Phase Synthesis
methodNMR, 20 Structures
similarity Belongs to the groes chaperonin family.[Cpn10]
subunit Heptamer of 7 subunits arranged in a ring (by similarity).
subcellular loc. Cytoplasm (by similarity).
gene MT3527 (M. tuberculosis)
function Binds to cpn60 in the presence of mg-atp and suppresses the atpase activity of the latter.
Gene
Ontology
ChainFunctionProcessComponent
A
  • ATP binding
  • unfolded protein binding
  • protein folding
  • response to unfolded protein...

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