ApoCanD

#	Name/ID	Cell Line/Tumor sample	Tissue of Origin	Reference ID	cDNA change	Protein change	Source	FATHMM Prediction	PolyPhen2 Prediction
1	IGROV1	Cell Line	OVARY	NP_932070	c.451C>A	p.L151M	CCLE	PASSENGER/OTHER	Benign
2	KE97	Cell Line	HAEMATOPOIETIC AND LYMPHOID TISSUE	NP_932070	c.501_splice	p.E167_splice	CCLE	NP	NP
3	MFE319	Cell Line	ENDOMETRIUM	NP_932070	c.47_47delG	p.G16fs	CCLE	NP	NP
4	NCIH2106	Cell Line	LUNG	NP_932070	c.694G>T	p.V232L	CCLE	NP	NP
5	PANC0327	Cell Line	PANCREAS	NP_932070	c.362_splice	p.D121_splice	CCLE	NP	NP
6	TCGA-24-1423-01	Tumour	OVARY	ENST00000317361	c.329G>C	p.S110T	COSMIC	NP	NP
7	TCGA-A6-2676-01	Tumour	LARGE INTESTINE	ENST00000317361	c.421G>A	p.D141N	COSMIC	NP	NP
8	TCGA-AG-A002-01	Tumour	LARGE INTESTINE	ENST00000317361	c.648C>A	p.V216V	COSMIC	NP	NP

*NP: Not Predicted

Expression and CNV data is not present for BID!!

Note: Lower the GARP score (more negative), higher the essentiality of the gene. P-value tells about the significane of GARP score.

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Modelled Structure	Structures available in PDB

1. PFAM domains are not present!!

2. Superfaimly domains are not present!!

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1. Sequence alignment with 1000 genome variations:

2. Sequence alignment with CCLE mutants:

3. Sequence alignment with COSMIC mutants:

4. Sequence alignment with homologus proteins:

HMM
With Uniprot database	With Mutants	With 1000 Genome Variants

PSSM
With Uniprot database	With Mutants	With 1000 Genome Variant

Post translational modifications are not found!!

Protein: BID