Protein: CASP3 |
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# | Name/ID | Cell Line/Tumor sample | Tissue of Origin | Reference ID | cDNA change | Protein change | Source | FATHMM Prediction | PolyPhen2 Prediction |
---|---|---|---|---|---|---|---|---|---|
1 | CW2 | Cell Line | LARGE INTESTINE | NP_004337 | c.415_416insA | p.I139fs | CCLE | NP | NP |
2 | CW2 | Cell Line | LARGE INTESTINE | NP_004337 | c.491G>A | p.R164H | CCLE | PASSENGER/OTHER | Probably Damaging |
3 | DBTRG05MG | Cell Line | CENTRAL NERVOUS SYSTEM | NP_004337 | c.478A>T | p.I160F | CCLE | PASSENGER/OTHER | Probably Damaging |
4 | DMS79 | Cell Line | LUNG | NP_004337 | c.167A>G | p.H56R | CCLE | PASSENGER/OTHER | Benign |
5 | HEC251 | Cell Line | ENDOMETRIUM | NP_004337 | c.824T>G | p.F275C | CCLE | PASSENGER/OTHER | Probably Damaging |
6 | HS578T | Cell Line | BREAST | NP_004337 | c.60C>G | p.I20M | CCLE | PASSENGER/OTHER | Benign |
7 | JHUEM2 | Cell Line | ENDOMETRIUM | NP_004337 | c.662C>T | p.A221V | CCLE | PASSENGER/OTHER | Benign |
8 | RKO | Cell Line | LARGE INTESTINE | NP_004337 | c.415_415delA | p.I139fs | CCLE | NP | NP |
9 | HCC2998 | Cell Line | LARGE INTESTINE | ENST00000308394 | c.814G>T | p.E272* | COSMIC | NP | NP |
10 | LUAD-B02594 | Tumour | LUNG | ENST00000308394 | c.295T>A | p.L99M | COSMIC | NP | NP |
11 | LUAD-QCHM7 | Tumour | LUNG | ENST00000308394 | c.429C>T | p.F143F | COSMIC | NP | NP |
12 | LUAD-S01315 | Tumour | LUNG | ENST00000308394 | c.197G>T | p.G66V | COSMIC | NP | NP |
13 | P04-2599 | Tumour | PROSTATE | ENST00000308394 | c.825T>A | p.F275L | COSMIC | NP | NP |
14 | PD2166a | Tumour | KIDNEY | ENST00000308394 | c.483+1G>A | p.? | COSMIC | NP | NP |
15 | S00472 | Tumour | LUNG | ENST00000308394 | c.415A>G | p.I139V | COSMIC | NP | NP |
16 | TCGA-38-4631-01 | Tumour | LUNG | ENST00000308394 | c.482A>T | p.Q161L | COSMIC | NP | NP |
17 | TCGA-44-7671-01 | Tumour | LUNG | ENST00000308394 | c.343G>T | p.V115F | COSMIC | NP | NP |
18 | TCGA-44-7672-01 | Tumour | LUNG | ENST00000308394 | c.831C>G | p.H277Q | COSMIC | NP | NP |
19 | TCGA-91-6835-01 | Tumour | LUNG | ENST00000308394 | c.481C>T | p.Q161* | COSMIC | NP | NP |
20 | TCGA-A6-6141-01 | Tumour | LARGE INTESTINE | ENST00000308394 | c.159G>T | p.K53N | COSMIC | NP | NP |
21 | TCGA-AA-3977-01 | Tumour | LARGE INTESTINE | ENST00000308394 | c.207C>T | p.V69V | COSMIC | NP | NP |
22 | TCGA-AA-A010-01 | Tumour | LARGE INTESTINE | ENST00000308394 | c.268G>T | p.D90Y | COSMIC | NP | NP |
23 | TCGA-AB-2854-03 | Tumour | HAEMATOPOIETIC AND LYMPHOID TISSUE | ENST00000308394 | c.730G>A | p.A244T | COSMIC | NP | NP |
24 | TCGA-AG-A002-01 | Tumour | LARGE INTESTINE | ENST00000308394 | c.428T>C | p.F143S | COSMIC | NP | NP |
25 | TCGA-AP-A059-01 | Tumour | ENDOMETRIUM | ENST00000308394 | c.619C>T | p.R207* | COSMIC | NP | NP |
26 | TCGA-AX-A0J0-01 | Tumour | ENDOMETRIUM | ENST00000308394 | c.340T>G | p.F114V | COSMIC | NP | NP |
27 | TCGA-B5-A0JY-01 | Tumour | ENDOMETRIUM | ENST00000308394 | c.321T>C | p.D107D | COSMIC | NP | NP |
28 | TCGA-B5-A0K9-01 | Tumour | ENDOMETRIUM | ENST00000308394 | c.72C>T | p.S24S | COSMIC | NP | NP |
29 | TCGA-BS-A0UF-01 | Tumour | ENDOMETRIUM | ENST00000308394 | c.352C>A | p.L118I | COSMIC | NP | NP |
30 | TCGA-BS-A0UF-01 | Tumour | ENDOMETRIUM | ENST00000308394 | c.574G>A | p.D192N | COSMIC | NP | NP |
31 | TCGA-D1-A16Y-01 | Tumour | ENDOMETRIUM | ENST00000308394 | c.207C>T | p.V69V | COSMIC | NP | NP |
32 | TCGA-DK-A2I1-01 | Tumour | URINARY TRACT | ENST00000308394 | c.538G>C | p.D180H | COSMIC | NP | NP |
33 | TCGA-G4-6586-01 | Tumour | LARGE INTESTINE | ENST00000308394 | c.721C>T | p.R241* | COSMIC | NP | NP |
34 | cSCCP8 | Tumour | SKIN | ENST00000308394 | c.385G>T | p.G129* | COSMIC | NP | NP |
35 | ccRCC-38 | Tumour | KIDNEY | ENST00000308394 | c.542A>C | p.D181A | COSMIC | NP | NP |
36 | CW2 | Cell Line | LARGE_INTESTINE | ENST00000308394 | c.415_416insA | p.I139fs*11 | COSMIC | NP | NP |
37 | CW2 | Cell Line | LARGE_INTESTINE | ENST00000308394 | c.491G>A | p.R164H | COSMIC | PASSENGER/OTHER | PROBABLY DAMAGING |
38 | DBTRG05MG | Cell Line | CENTRAL_NERVOUS_SYSTEM | ENST00000308394 | c.478A>T | p.I160F | COSMIC | PASSENGER/OTHER | PROBABLY DAMAGING |
39 | DMS79 | Cell Line | LUNG | ENST00000308394 | c.167A>G | p.H56R | COSMIC | PASSENGER/OTHER | BENIGN |
40 | EMCBAC1 | Cell Line | LUNG | ENST00000308394 | c.433G>T | p.G145W | COSMIC | PASSENGER/OTHER | PROBABLY DAMAGING |
41 | GP5D | Cell Line | LARGE_INTESTINE | ENST00000308394 | c.78A>G | p.S26S | COSMIC | NP | NP |
42 | HCC2998 | Cell Line | LARGE_INTESTINE | ENST00000308394 | c.814G>T | p.E272* | COSMIC | NP | NP |
43 | HS578T | Cell Line | BREAST | ENST00000308394 | c.60C>G | p.I20M | COSMIC | PASSENGER/OTHER | BENIGN |
44 | JURKAT | Cell Line | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | ENST00000308394 | c.102C>T | p.D34D | COSMIC | NP | NP |
45 | JURKAT | Cell Line | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | ENST00000308394 | c.570G>T | p.E190D | COSMIC | PASSENGER/OTHER | PROBABLY DAMAGING |
46 | K5 | Cell Line | THYROID | ENST00000308394 | c.96C>T | p.S32S | COSMIC | NP | NP |
47 | LNCAPCLONEFGC | Cell Line | PROSTATE | ENST00000308394 | c.604+8C>T | p.? | COSMIC | NP | NP |
48 | LS411N | Cell Line | LARGE_INTESTINE | ENST00000308394 | c.525C>T | p.D175D | COSMIC | NP | NP |
49 | MCF7 | Cell Line | BREAST | ENST00000308394 | c.84_130del47 | p.S29fs*7 | COSMIC | NP | NP |
50 | MOLT4 | Cell Line | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | ENST00000308394 | c.301C>T | p.R101C | COSMIC | PASSENGER/OTHER | BENIGN |
51 | PF382 | Cell Line | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | ENST00000308394 | c.178+3A>G | p.? | COSMIC | NP | NP |
52 | SBC3 | Cell Line | LUNG | ENST00000308394 | c.604+8C>T | p.? | COSMIC | NP | NP |
53 | SCH | Cell Line | STOMACH | ENST00000308394 | c.698T>A | p.M233K | COSMIC | PASSENGER/OTHER | PROBABLY DAMAGING |
54 | TOV112D | Cell Line | OVARY | ENST00000308394 | c.142A>G | p.I48V | COSMIC | PASSENGER/OTHER | BENIGN |
Modelled Structure | Structures available in PDB |