Protein: CFLAR |
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# | Name/ID | Cell Line/Tumor sample | Tissue of Origin | Reference ID | cDNA change | Protein change | Source | FATHMM Prediction | PolyPhen2 Prediction |
---|---|---|---|---|---|---|---|---|---|
1 | GC1 | Tumour | T STOMACH | ENST00000309955 | c.877C>G | p.L293V | COSMIC | NP | NP |
2 | LUAD-B02477 | Tumour | LUNG | ENST00000309955 | c.162C>G | p.D54E | COSMIC | NP | NP |
3 | LUAD-S01345 | Tumour | LUNG | ENST00000309955 | c.1031C>T | p.S344L | COSMIC | NP | NP |
4 | PD3904a | Tumour | BREAST | ENST00000309955 | c.1093G>T | p.G365C | COSMIC | NP | NP |
5 | TCGA-37-4135-01 | Tumour | LUNG | ENST00000309955 | c.1171G>T | p.G391W | COSMIC | NP | NP |
6 | TCGA-43-3920-01 | Tumour | LUNG | ENST00000309955 | c.1249C>A | p.H417N | COSMIC | NP | NP |
7 | TCGA-67-3771-01 | Tumour | LUNG | ENST00000309955 | c.45A>C | p.T15T | COSMIC | NP | NP |
8 | TCGA-73-4668-01 | Tumour | LUNG | ENST00000309955 | c.1264C>T | p.L422L | COSMIC | NP | NP |
9 | TCGA-AA-3977-01 | Tumour | LARGE INTESTINE | ENST00000309955 | c.1143G>T | p.K381N | COSMIC | NP | NP |
10 | TCGA-AA-A01Z-01 | Tumour | LARGE INTESTINE | ENST00000309955 | c.877C>A | p.L293I | COSMIC | NP | NP |
11 | TCGA-AB-2812-03 | Tumour | HAEMATOPOIETIC AND LYMPHOID TISSUE | ENST00000309955 | c.240G>A | p.E80E | COSMIC | NP | NP |
12 | TCGA-AG-A002-01 | Tumour | LARGE INTESTINE | ENST00000309955 | c.653G>A | p.G218D | COSMIC | NP | NP |
13 | TCGA-AP-A059-01 | Tumour | ENDOMETRIUM | ENST00000309955 | c.931G>A | p.V311I | COSMIC | NP | NP |
14 | TCGA-AX-A05Z-01 | Tumour | ENDOMETRIUM | ENST00000309955 | c.771C>T | p.I257I | COSMIC | NP | NP |
15 | TCGA-B0-4712-01 | Tumour | KIDNEY | ENST00000309955 | c.1028A>G | p.D343G | COSMIC | NP | NP |
16 | TCGA-BS-A0UF-01 | Tumour | ENDOMETRIUM | ENST00000309955 | c.1443A>G | p.*481* | COSMIC | NP | NP |
17 | TCGA-BS-A0UV-01 | Tumour | ENDOMETRIUM | ENST00000309955 | c.653G>A | p.G218D | COSMIC | NP | NP |
18 | TCGA-C8-A275-01 | Tumour | BREAST | ENST00000309955 | c.288G>T | p.L96L | COSMIC | NP | NP |
19 | TCGA-DS-A1OD-01 | Tumour | CERVIX | ENST00000309955 | c.934C>A | p.L312M | COSMIC | NP | NP |
20 | TCGA-G2-A3IE-01 | Tumour | URINARY TRACT | ENST00000309955 | c.957G>A | p.Q319Q | COSMIC | NP | NP |
21 | TCGA-H4-A2HQ-01 | Tumour | URINARY TRACT | ENST00000309955 | c.409G>A | p.E137K | COSMIC | NP | NP |
22 | YUGOE | Tumour | SKIN | ENST00000309955 | c.31G>A | p.E11K | COSMIC | NP | NP |
23 | 639V | Cell Line | URINARY_TRACT | ENST00000309955 | c.133C>T | p.R45W | COSMIC | CANCER | PROBABLY DAMAGING |
24 | ACN | Cell Line | AUTONOMIC_GANGLIA | ENST00000309955 | c.609C>T | p.L203L | COSMIC | NP | NP |
25 | AM38 | Cell Line | CENTRAL_NERVOUS_SYSTEM | ENST00000309955 | c.21T>C | p.H7H | COSMIC | NP | NP |
26 | ARH77 | Cell Line | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | ENST00000309955 | c.1137G>C | p.A379A | COSMIC | NP | NP |
27 | CHL1 | Cell Line | SKIN | ENST00000309955 | c.707C>T | p.P236L | COSMIC | PASSENGER/OTHER | BENIGN |
28 | CORL95 | Cell Line | LUNG | ENST00000309955 | c.586G>T | p.D196Y | COSMIC | PASSENGER/OTHER | PROBABLY DAMAGING |
29 | DU145 | Cell Line | PROSTATE | ENST00000309955 | c.606+7C>A | p.? | COSMIC | NP | NP |
30 | EOL1CELL | Cell Line | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | ENST00000309955 | c.280_282-3del2882 | p.? | COSMIC | NP | NP |
31 | FTC133 | Cell Line | THYROID | ENST00000309955 | c.958A>G | p.S320G | COSMIC | PASSENGER/OTHER | BENIGN |
32 | GP5D | Cell Line | LARGE_INTESTINE | ENST00000309955 | c.33A>G | p.E11E | COSMIC | NP | NP |
33 | HCC2998 | Cell Line | LARGE_INTESTINE | ENST00000309955 | c.363C>T | p.G121G | COSMIC | NP | NP |
34 | HCC827 | Cell Line | LUNG | ENST00000309955 | c.1035C>T | p.C345C | COSMIC | NP | NP |
35 | HEC1 | Cell Line | ENDOMETRIUM | ENST00000309955 | c.381G>T | p.K127N | COSMIC | CANCER | PROBABLY DAMAGING |
36 | HMVII | Cell Line | SKIN | ENST00000309955 | c.829G>A | p.E277K | COSMIC | PASSENGER/OTHER | BENIGN |
37 | HOS | Cell Line | BONE | ENST00000309955 | c.798T>G | p.L266L | COSMIC | NP | NP |
38 | HT | Cell Line | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | ENST00000309955 | c.1292T>C | p.L431P | COSMIC | PASSENGER/OTHER | PROBABLY DAMAGING |
39 | JURKAT | Cell Line | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | ENST00000309955 | c.1395C>T | p.V465V | COSMIC | NP | NP |
40 | LP1 | Cell Line | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | ENST00000309955 | c.613A>G | p.N205D | COSMIC | PASSENGER/OTHER | POSSIBLY DAMAGING |
41 | MDAMB231 | Cell Line | BREAST | ENST00000309955 | c.1223C>T | p.A408V | COSMIC | PASSENGER/OTHER | BENIGN |
42 | MZ1PC | Cell Line | PANCREAS | ENST00000309955 | c.241A>C | p.T81P | COSMIC | PASSENGER/OTHER | BENIGN |
43 | NB10 | Cell Line | AUTONOMIC_GANGLIA | ENST00000309955 | c.240G>T | p.E80D | COSMIC | PASSENGER/OTHER | PROBABLY DAMAGING |
44 | NUGC4 | Cell Line | STOMACH | ENST00000309955 | c.388-3_388-2insA | p.? | COSMIC | NP | NP |
45 | RCCAB | Cell Line | KIDNEY | ENST00000309955 | c.1398G>C | p.W466C | COSMIC | PASSENGER/OTHER | BENIGN |
46 | RCCJF | Cell Line | KIDNEY | ENST00000309955 | c.1115T>A | p.L372H | COSMIC | PASSENGER/OTHER | PROBABLY DAMAGING |
47 | RERFLCFM | Cell Line | LUNG | ENST00000309955 | c.1294A>C | p.R432R | COSMIC | NP | NP |
48 | SNUC2B | Cell Line | LARGE_INTESTINE | ENST00000309955 | c.198C>T | p.D66D | COSMIC | NP | NP |
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S. No. | Position | Amino acid | Type | Description |
1 | 192 | K | Ubiquitylation | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) |
2 | 193 | S | Phosphorylation | Phosphoserine |
3 | 254 | C | S-nitrosylation | S-nitrosocysteine |
4 | 259 | C | S-nitrosylation | S-nitrosocysteine |
5 | 273 | S | Phosphorylation | Phosphoserine |
6 | 376 | D | Proteolytic Cleavage | none |
Proteomics DB | COSMIC | Gene Atlas | STRING | PIR |
CFLAR | CFLAR | CFLAR | ENSP00000312455 | O15519 |
QuickGO | HGNC | Ensembl Genome Browser | TreeFam | UniProt |
O15519 | CFLAR | ENSP00000312455 | CFLAR | O15519 |
Expression Atlas | Protein Atlas | OMIM | IntAct | PharmGKB |
CFLAR | ENSP00000312455 | 603599 | O15519 | PA24733 |