Protein: HTRA2 |
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# | Name/ID | Cell Line/Tumor sample | Tissue of Origin | Reference ID | cDNA change | Protein change | Source | FATHMM Prediction | PolyPhen2 Prediction |
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1 | 587338 | Tumour | LARGE INTESTINE | ENST00000258080 | c.254C>T | p.A85V | COSMIC | NP | NP |
2 | 587376 | Tumour | LARGE INTESTINE | ENST00000258080 | c.782G>A | p.G261E | COSMIC | NP | NP |
3 | ESO-913 | Tumour | OESOPHAGUS | ENST00000258080 | c.1078C>T | p.R360C | COSMIC | NP | NP |
4 | LC | Tumour | C24 LUNG | ENST00000258080 | c.149T>G | p.V50G | COSMIC | NP | NP |
5 | LUAD-B00416 | Tumour | LUNG | ENST00000258080 | c.1349T>G | p.L450* | COSMIC | NP | NP |
6 | RK069 | Tumour | C01 LIVER | ENST00000258080 | c.1344G>C | p.L448L | COSMIC | NP | NP |
7 | TCGA-22-5474-01 | Tumour | LUNG | ENST00000258080 | c.70C>T | p.R24C | COSMIC | NP | NP |
8 | TCGA-25-1319-01 | Tumour | OVARY | ENST00000258080 | c.718C>T | p.L240F | COSMIC | NP | NP |
9 | TCGA-64-1678-01 | Tumour | LUNG | ENST00000258080 | c.1241T>A | p.L414* | COSMIC | NP | NP |
10 | TCGA-66-2785-01 | Tumour | LUNG | ENST00000258080 | c.835C>G | p.Q279E | COSMIC | NP | NP |
11 | TCGA-70-6722-01 | Tumour | LUNG | ENST00000258080 | c.12G>A | p.P4P | COSMIC | NP | NP |
12 | TCGA-91-6848-01 | Tumour | LUNG | ENST00000258080 | c.379G>T | p.G127C | COSMIC | NP | NP |
13 | TCGA-AA-3864-01 | Tumour | LARGE INTESTINE | ENST00000258080 | c.1031G>A | p.R344H | COSMIC | NP | NP |
14 | TCGA-AA-3949-01 | Tumour | LARGE INTESTINE | ENST00000258080 | c.191G>A | p.G64E | COSMIC | NP | NP |
15 | TCGA-AA-3977-01 | Tumour | LARGE INTESTINE | ENST00000258080 | c.1285G>T | p.E429* | COSMIC | NP | NP |
16 | TCGA-AX-A0J0-01 | Tumour | ENDOMETRIUM | ENST00000258080 | c.1295G>A | p.R432Q | COSMIC | NP | NP |
17 | TCGA-B5-A0JY-01 | Tumour | ENDOMETRIUM | ENST00000258080 | c.1138C>T | p.R380* | COSMIC | NP | NP |
18 | TCGA-B5-A11E-01 | Tumour | ENDOMETRIUM | ENST00000258080 | c.1078C>T | p.R360C | COSMIC | NP | NP |
19 | TCGA-BS-A0UF-01 | Tumour | ENDOMETRIUM | ENST00000258080 | c.1016G>A | p.R339Q | COSMIC | NP | NP |
20 | TCGA-CF-A1HR-01 | Tumour | URINARY TRACT | ENST00000258080 | c.12G>A | p.P4P | COSMIC | NP | NP |
21 | TCGA-D1-A167-01 | Tumour | ENDOMETRIUM | ENST00000258080 | c.1009C>A | p.R337S | COSMIC | NP | NP |
22 | cSCCP4 | Tumour | SKIN | ENST00000258080 | c.539C>G | p.S180W | COSMIC | NP | NP |
23 | ALLPO | Cell Line | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | ENST00000258080 | c.618C>G | p.V206V | COSMIC | NP | NP |
24 | CHP134 | Cell Line | AUTONOMIC_GANGLIA | ENST00000258080 | c.1258A>G | p.M420V | COSMIC | PASSENGER/OTHER | BENIGN |
25 | COLO792 | Cell Line | SKIN | ENST00000258080 | c.1212-1G>A | p.? | COSMIC | NP | NP |
26 | GP5D | Cell Line | LARGE_INTESTINE | ENST00000258080 | c.1324C>T | p.R442W | COSMIC | PASSENGER/OTHER | PROBABLY DAMAGING |
27 | GP5D | Cell Line | LARGE_INTESTINE | ENST00000258080 | c.573G>A | p.G191G | COSMIC | NP | NP |
28 | JURKAT | Cell Line | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | ENST00000258080 | c.71G>A | p.R24H | COSMIC | PASSENGER/OTHER | BENIGN |
29 | KARPAS45 | Cell Line | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | ENST00000258080 | c.114G>A | p.L38L | COSMIC | NP | NP |
30 | MCC13 | Cell Line | SKIN | ENST00000258080 | c.507-8C>T | p.? | COSMIC | NP | NP |
31 | MFE280 | Cell Line | ENDOMETRIUM | ENST00000258080 | c.1233T>G | p.D411E | COSMIC | CANCER | POSSIBLY DAMAGING |
32 | MFM223 | Cell Line | BREAST | ENST00000258080 | c.506+5_506+7delTGG | p.? | COSMIC | NP | NP |
33 | MOLT4 | Cell Line | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | ENST00000258080 | c.688G>A | p.A230T | COSMIC | CANCER | PROBABLY DAMAGING |
34 | NALM6 | Cell Line | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | ENST00000258080 | c.518T>G | p.L173W | COSMIC | PASSENGER/OTHER | PROBABLY DAMAGING |
35 | NCCIT | Cell Line | TESTIS | ENST00000258080 | c.123A>T | p.S41S | COSMIC | NP | NP |
36 | NCIH1734 | Cell Line | LUNG | ENST00000258080 | c.935A>T | p.N312I | COSMIC | PASSENGER/OTHER | PROBABLY DAMAGING |
37 | RCCJF | Cell Line | KIDNEY | ENST00000258080 | c.879A>G | p.E293E | COSMIC | NP | NP |
38 | SNU175 | Cell Line | LARGE_INTESTINE | ENST00000258080 | c.1079G>A | p.R360H | COSMIC | PASSENGER/OTHER | PROBABLY DAMAGING |
39 | SUPB15 | Cell Line | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | ENST00000258080 | c.1057G>C | p.G353R | COSMIC | PASSENGER/OTHER | PROBABLY DAMAGING |
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S. No. | Position | Amino acid | Type | Description |
1 | 142 | S | Phosphorylation | Phosphoserine |
2 | 212 | S | Phosphorylation | Phosphoserine |
3 | 237 | K | Ubiquitylation | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) |
4 | 361 | Y | Phosphorylation | Phosphotyrosine |
5 | 395 | K | Ubiquitylation | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) |
6 | 400 | S | Phosphorylation | Phosphoserine |
7 | 51 | T | Phosphorylation | Phosphothreonine |
8 | 54 | T | Phosphorylation | Phosphothreonine |
Proteomics DB | COSMIC | Gene Atlas | STRING | PIR |
HTRA2 | HTRA2 | HTRA2 | ENSP00000258080 | O43464 |
QuickGO | HGNC | Ensembl Genome Browser | TreeFam | UniProt |
O43464 | HTRA2 | ENSP00000258080 | HTRA2 | O43464 |
Expression Atlas | Protein Atlas | OMIM | IntAct | PharmGKB |
HTRA2 | ENSP00000258080 | 606441 | O43464 | PA33836 |