Protein: MCL1 |
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# | Name/ID | Cell Line/Tumor sample | Tissue of Origin | Reference ID | cDNA change | Protein change | Source | FATHMM Prediction | PolyPhen2 Prediction |
---|---|---|---|---|---|---|---|---|---|
1 | EB2 | Cell Line | HAEMATOPOIETIC AND LYMPHOID TISSUE | NP_068779 | c.217T>C | p.S73P | CCLE | PASSENGER/OTHER | Benign |
2 | HEC108 | Cell Line | ENDOMETRIUM | NP_068779 | c.44A>G | p.Y15C | CCLE | PASSENGER/OTHER | Probably Damaging |
3 | HEC1A | Cell Line | ENDOMETRIUM | NP_068779 | c.55_56insG | p.A19fs | CCLE | NP | NP |
4 | HEC6 | Cell Line | ENDOMETRIUM | NP_068779 | c.671A>G | p.H224R | CCLE | PASSENGER/OTHER | Probably Damaging |
5 | HS618T | Cell Line | LUNG | NP_068779 | c.328_330delGAG | p.E110del | CCLE | NP | NP |
6 | MEWO | Cell Line | SKIN | NP_068779 | c.219C>T | p.S73S | CCLE | NP | NP |
7 | NCIH1563 | Cell Line | LUNG | NP_068779 | c.282G>A | p.A94A | CCLE | NP | NP |
8 | REH | Cell Line | HAEMATOPOIETIC AND LYMPHOID TISSUE | NP_068779 | c.221G>A | p.R74Q | CCLE | PASSENGER/OTHER | Benign |
9 | SUDHL5 | Cell Line | HAEMATOPOIETIC AND LYMPHOID TISSUE | NP_068779 | c.43T>C | p.Y15H | CCLE | PASSENGER/OTHER | Possibly Damaging |
10 | SUDHL5 | Cell Line | HAEMATOPOIETIC AND LYMPHOID TISSUE | NP_068779 | c.990T>C | p.N330N | CCLE | NP | NP |
11 | SW1783 | Cell Line | CENTRAL NERVOUS SYSTEM | NP_068779 | c.1031G>T | p.G344V | CCLE | PASSENGER/OTHER | Probably Damaging |
12 | 1990619 | Tumour | EYE | ENST00000369026 | c.278C>G | p.P93R | COSMIC | NP | NP |
13 | 587224 | Tumour | LARGE INTESTINE | ENST00000369026 | c.442G>A | p.G148R | COSMIC | NP | NP |
14 | ESO-837 | Tumour | OESOPHAGUS | ENST00000369026 | c.660G>A | p.V220V | COSMIC | NP | NP |
15 | H1155 | Cell Line | LUNG | ENST00000369026 | c.643C>G | p.R215G | COSMIC | NP | NP |
16 | LUAD-B00859 | Tumour | LUNG | ENST00000369026 | c.57C>A | p.A19A | COSMIC | NP | NP |
17 | LUAD-CHTN-MAD06-00668 | Tumour | LUNG | ENST00000369026 | c.590A>T | p.K197M | COSMIC | NP | NP |
18 | LUAD-S01315 | Tumour | LUNG | ENST00000369026 | c.1042C>G | p.L348V | COSMIC | NP | NP |
19 | PD6749a | Tumour | NS | ENST00000369026 | c.583G>T | p.D195Y | COSMIC | NP | NP |
20 | TCGA-33-4547-01 | Tumour | LUNG | ENST00000369026 | c.559C>T | p.R187W | COSMIC | NP | NP |
21 | TCGA-39-5028-01 | Tumour | LUNG | ENST00000369026 | c.367G>A | p.E123K | COSMIC | NP | NP |
22 | TCGA-55-6979-01 | Tumour | LUNG | ENST00000369026 | c.699G>C | p.R233R | COSMIC | NP | NP |
23 | TCGA-85-6561-01 | Tumour | LUNG | ENST00000369026 | c.894C>A | p.L298L | COSMIC | NP | NP |
24 | TCGA-97-7546-01 | Tumour | LUNG | ENST00000369026 | c.315G>T | p.A105A | COSMIC | NP | NP |
25 | TCGA-AA-3811-01 | Tumour | LARGE INTESTINE | ENST00000369026 | c.804T>C | p.I268I | COSMIC | NP | NP |
26 | TCGA-BG-A0LX-01 | Tumour | ENDOMETRIUM | ENST00000369026 | c.970C>A | p.L324I | COSMIC | NP | NP |
27 | TCGA-BS-A0UF-01 | Tumour | ENDOMETRIUM | ENST00000369026 | c.520T>C | p.L174L | COSMIC | NP | NP |
28 | TCGA-BS-A0UF-01 | Tumour | ENDOMETRIUM | ENST00000369026 | c.870A>C | p.L290F | COSMIC | NP | NP |
29 | TCGA-D1-A177-01 | Tumour | ENDOMETRIUM | ENST00000369026 | c.441C>T | p.V147V | COSMIC | NP | NP |
30 | TCGA-D8-A1JN-01 | Tumour | BREAST | ENST00000369026 | c.724G>A | p.D242N | COSMIC | NP | NP |
31 | TCGA-D8-A1XO-01 | Tumour | BREAST | ENST00000369026 | c.648T>A | p.V216V | COSMIC | NP | NP |
32 | TCGA-DK-A1AC-01 | Tumour | URINARY TRACT | ENST00000369026 | c.882C>T | p.I294I | COSMIC | NP | NP |
33 | TCGA-EJ-5542-01 | Tumour | PROSTATE | ENST00000369026 | c.652G>A | p.D218N | COSMIC | NP | NP |
34 | TCGA-G2-A2EJ-01 | Tumour | URINARY TRACT | ENST00000369026 | c.559C>T | p.R187W | COSMIC | NP | NP |
35 | TCGA-H4-A2HQ-01 | Tumour | URINARY TRACT | ENST00000369026 | c.282G>C | p.A94A | COSMIC | NP | NP |
36 | tumor | Tumour | 4163639 HAEMATOPOIETIC AND LYMPHOID TISSUE | ENST00000369026 | c.481C>T | p.P161S | COSMIC | NP | NP |
37 | CTB1 | Cell Line | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | ENST00000369026 | c.555C>T | p.Y185Y | COSMIC | NP | NP |
38 | CTB1 | Cell Line | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | ENST00000369026 | c.788G>A | p.R263K | COSMIC | PASSENGER/OTHER | PROBABLY DAMAGING |
39 | EB2 | Cell Line | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | ENST00000369026 | c.688+10T>A | p.? | COSMIC | NP | NP |
40 | ECC10 | Cell Line | STOMACH | ENST00000369026 | c.24G>T | p.A8A | COSMIC | NP | NP |
41 | EN | Cell Line | ENDOMETRIUM | ENST00000369026 | c.55_56insGGG | p.G18 | COSMIC | NP | NP |
42 | HCC2998 | Cell Line | LARGE_INTESTINE | ENST00000369026 | c.520T>C | p.L174L | COSMIC | NP | NP |
43 | HS940T | Cell Line | SKIN | ENST00000369026 | c.543T>C | p.I181I | COSMIC | NP | NP |
44 | KARPAS45 | Cell Line | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | ENST00000369026 | c.706G>T | p.D236Y | COSMIC | PASSENGER/OTHER | PROBABLY DAMAGING |
45 | KARPAS45 | Cell Line | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | ENST00000369026 | c.766G>A | p.D256N | COSMIC | PASSENGER/OTHER | PROBABLY DAMAGING |
46 | NCIH1155 | Cell Line | LUNG | ENST00000369026 | c.643C>G | p.R215G | COSMIC | PASSENGER/OTHER | POSSIBLY DAMAGING |
47 | NCIH2081 | Cell Line | LUNG | ENST00000369026 | c.498A>T | p.P166P | COSMIC | NP | NP |
48 | PE/CAPJ15 | Cell Line | UPPER_AERODIGESTIVE_TRACT | ENST00000369026 | c.402C>G | p.L134L | COSMIC | NP | NP |
49 | SNU1040 | Cell Line | LARGE_INTESTINE | ENST00000369026 | c.577G>A | p.A193T | COSMIC | PASSENGER/OTHER | BENIGN |
50 | SNU175 | Cell Line | LARGE_INTESTINE | ENST00000369026 | c.430C>T | p.L144L | COSMIC | NP | NP |
51 | SUDHL5 | Cell Line | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | ENST00000369026 | c.43T>C | p.Y15H | COSMIC | PASSENGER/OTHER | POSSIBLY DAMAGING |
52 | SUDHL5 | Cell Line | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | ENST00000369026 | c.990T>C | p.N330N | COSMIC | NP | NP |
53 | SW1783 | Cell Line | CENTRAL_NERVOUS_SYSTEM | ENST00000369026 | c.510G>A | p.E170E | COSMIC | NP | NP |
Modelled Structure | Structures available in PDB |