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3163 details
Primary information
CancerPPD ID3163
PMID23301519
YEAR2013
SEQUENCERWRWRWRW
LENGTH8
NAMElinear (RW)4-Dox
C-ter ModificationFree
N-ter ModificationFree
Linear/CyclicLinear
L/D/MixL
Non-NaturalDoxorubicin (Dox) which is anthracycline attached with linker to CPP [W(RW)4 ]
NATUREAnticancer
ACTIVITY21-61% antiproliferative activity at 1 µM
SOURCEDoxorubicin (Dox) is a well-known anthracycline which has been conjugated to a CPP
ASSAYMTT/MTS assay
CELL LINEHCT-116
TEST TIME72 to 120-h
Secondary information
STRUCTURE
Predicted Structure
DSSP statesNA
SMILESNA
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
NANANANANANANANA