Cancertope
In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer
Personalized immunotherapy or Vaccine against Cancer
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The result page of search shows exclusive peptide/epitopes generated due to mutation [Neoepitope], the tissue of origin [Tissue], position of peptide in protein [Position], number of mismatches counted by aligning mutated and normal protein sequence [Num Mismatch, percentage of cell lines with this peptide over total number of cell lines [Promiscuity %]. The immune information include CTL epitopes (Yes/No), MHC I binders, MHC II binders (both given as number of alleles) and B cell epitopes (Yes/No). For more information, please click |
| Result | Search: | |||||||||||||||||||||||||
| Protein | Neoepitopes | Tissue | Position | Prot Mutation | cDNA Mutation | Mutation Type | Num Mismatch | Promiscuity (%) | Cell Line | CTL | MHC I | NHLApred | MHC II | Bcell | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CREB3L2 | ARSLGPSRP | STOMACH | 86 | p.A74fs | c.220_220delG | Frame_Shift_Del | 5 | 0.11 | MKN74 | N | 1 | 0 | 0 | N | ||||||||||||
| CREB3L2 | ASMTMRWKV | STOMACH | 103 | p.A74fs | c.220_220delG | Frame_Shift_Del | 6 | 0.11 | MKN74 | N | 4 | 0 | 0 | N | ||||||||||||
| CREB3L2 | ATPCARSLG | STOMACH | 82 | p.A74fs | c.220_220delG | Frame_Shift_Del | 5 | 0.11 | MKN74 | N | 0 | 0 | 0 | N | ||||||||||||
| CREB3L2 | CARSLGPSR | STOMACH | 85 | p.A74fs | c.220_220delG | Frame_Shift_Del | 6 | 0.11 | MKN74 | N | 3 | 0 | 0 | N | ||||||||||||
| CREB3L2 | GPSRPSPTL | STOMACH | 90 | p.A74fs | c.220_220delG | Frame_Shift_Del | 5 | 0.11 | MKN74 | N | 17 | 0 | 0 | Y | ||||||||||||
| CREB3L2 | GTCLQTSLQ | STOMACH | 114 | p.A74fs | c.220_220delG | Frame_Shift_Del | 5 | 0.11 | MKN74 | N | 0 | 0 | 0 | N | ||||||||||||
| CREB3L2 | HPQDSFRLS | STOMACH | 134 | p.A74fs | c.220_220delG | Frame_Shift_Del | 6 | 0.11 | MKN74 | N | 5 | 0 | 0 | N | ||||||||||||
| CREB3L2 | HPSRQSQLQ | STOMACH | 123 | p.A74fs | c.220_220delG | Frame_Shift_Del | 6 | 0.11 | MKN74 | N | 1 | 0 | 0 | Y | ||||||||||||
| CREB3L2 | KVRNGTCLQ | STOMACH | 110 | p.A74fs | c.220_220delG | Frame_Shift_Del | 5 | 0.11 | MKN74 | N | 0 | 0 | 0 | N | ||||||||||||
| CREB3L2 | LGPSRPSPT | STOMACH | 89 | p.A74fs | c.220_220delG | Frame_Shift_Del | 5 | 0.11 | MKN74 | N | 1 | 0 | 0 | Y | ||||||||||||
| CREB3L2 | LPPVTASMT | STOMACH | 98 | p.A74fs | c.220_220delG | Frame_Shift_Del | 5 | 0.11 | MKN74 | N | 6 | 0 | 0 | N | ||||||||||||
| CREB3L2 | LQHPSRQSQ | STOMACH | 121 | p.A74fs | c.220_220delG | Frame_Shift_Del | 5 | 0.11 | MKN74 | N | 0 | 0 | 0 | N | ||||||||||||
| CREB3L2 | LQTNHPQDS | STOMACH | 130 | p.A74fs | c.220_220delG | Frame_Shift_Del | 5 | 0.11 | MKN74 | N | 0 | 0 | 12 | N | ||||||||||||
| CREB3L2 | LSTATPCAR | STOMACH | 79 | p.A74fs | c.220_220delG | Frame_Shift_Del | 5 | 0.11 | MKN74 | N | 3 | 0 | 0 | N | ||||||||||||
| CREB3L2 | MRWKVRNGT | STOMACH | 107 | p.A74fs | c.220_220delG | Frame_Shift_Del | 6 | 0.11 | MKN74 | N | 3 | 0 | 17 | N | ||||||||||||
| CREB3L2 | MTMRWKVRN | STOMACH | 105 | p.A74fs | c.220_220delG | Frame_Shift_Del | 6 | 0.11 | MKN74 | N | 0 | 0 | 7 | N | ||||||||||||
| CREB3L2 | NGTCLQTSL | STOMACH | 113 | p.A74fs | c.220_220delG | Frame_Shift_Del | 5 | 0.11 | MKN74 | N | 8 | 0 | 0 | N | ||||||||||||
| CREB3L2 | NHPQDSFRL | STOMACH | 133 | p.A74fs | c.220_220delG | Frame_Shift_Del | 6 | 0.11 | MKN74 | N | 6 | 0 | 0 | N | ||||||||||||
| CREB3L2 | PCARSLGPS | STOMACH | 84 | p.A74fs | c.220_220delG | Frame_Shift_Del | 5 | 0.11 | MKN74 | N | 0 | 0 | 0 | N | ||||||||||||
| CREB3L2 | PPVTASMTM | STOMACH | 99 | p.A74fs | c.220_220delG | Frame_Shift_Del | 5 | 0.11 | MKN74 | N | 7 | 0 | 0 | N | ||||||||||||
| CREB3L2 | PQDSFRLSL | STOMACH | 135 | p.A74fs | c.220_220delG | Frame_Shift_Del | 5 | 0.11 | MKN74 | N | 3 | 0 | 0 | N | ||||||||||||
| CREB3L2 | PSRQSQLQT | STOMACH | 124 | p.A74fs | c.220_220delG | Frame_Shift_Del | 6 | 0.11 | MKN74 | N | 0 | 0 | 0 | N | ||||||||||||
| CREB3L2 | PTLPPVTAS | STOMACH | 96 | p.A74fs | c.220_220delG | Frame_Shift_Del | 5 | 0.11 | MKN74 | N | 0 | 0 | 0 | N | ||||||||||||
| CREB3L2 | PTSPRLSSR | STOMACH | 70 | p.A74fs | c.220_220delG | Frame_Shift_Del | 5 | 0.11 | MKN74 | N | 1 | 0 | 0 | N | ||||||||||||
| CREB3L2 | PVTASMTMR | STOMACH | 100 | p.A74fs | c.220_220delG | Frame_Shift_Del | 5 | 0.11 | MKN74 | N | 3 | 0 | 0 | N | ||||||||||||
| CREB3L2 | QHPSRQSQL | STOMACH | 122 | p.A74fs | c.220_220delG | Frame_Shift_Del | 6 | 0.11 | MKN74 | N | 7 | 0 | 0 | Y | ||||||||||||
| CREB3L2 | QLQTNHPQD | STOMACH | 129 | p.A74fs | c.220_220delG | Frame_Shift_Del | 6 | 0.11 | MKN74 | N | 1 | 0 | 0 | Y | ||||||||||||
| CREB3L2 | QSQLQTNHP | STOMACH | 127 | p.A74fs | c.220_220delG | Frame_Shift_Del | 5 | 0.11 | MKN74 | N | 0 | 0 | 0 | Y | ||||||||||||
| CREB3L2 | QTNHPQDSF | STOMACH | 131 | p.A74fs | c.220_220delG | Frame_Shift_Del | 6 | 0.11 | MKN74 | N | 3 | 0 | 0 | N | ||||||||||||
| CREB3L2 | RLSTATPCA | STOMACH | 78 | p.A74fs | c.220_220delG | Frame_Shift_Del | 5 | 0.11 | MKN74 | N | 5 | 0 | 0 | N | ||||||||||||
| CREB3L2 | RNGTCLQTS | STOMACH | 112 | p.A74fs | c.220_220delG | Frame_Shift_Del | 5 | 0.11 | MKN74 | N | 0 | 0 | 0 | N | ||||||||||||
| CREB3L2 | RQSQLQTNH | STOMACH | 126 | p.A74fs | c.220_220delG | Frame_Shift_Del | 6 | 0.11 | MKN74 | N | 2 | 0 | 0 | N | ||||||||||||
| CREB3L2 | RSLGPSRPS | STOMACH | 87 | p.A74fs | c.220_220delG | Frame_Shift_Del | 5 | 0.11 | MKN74 | N | 2 | 0 | 0 | N | ||||||||||||
| CREB3L2 | RWKVRNGTC | STOMACH | 108 | p.A74fs | c.220_220delG | Frame_Shift_Del | 6 | 0.11 | MKN74 | N | 1 | 0 | 0 | N | ||||||||||||
| CREB3L2 | SLGPSRPSP | STOMACH | 88 | p.A74fs | c.220_220delG | Frame_Shift_Del | 5 | 0.11 | MKN74 | N | 0 | 0 | 0 | N | ||||||||||||
| CREB3L2 | SMTMRWKVR | STOMACH | 104 | p.A74fs | c.220_220delG | Frame_Shift_Del | 6 | 0.11 | MKN74 | N | 4 | 0 | 0 | N | ||||||||||||
| CREB3L2 | SPTLPPVTA | STOMACH | 95 | p.A74fs | c.220_220delG | Frame_Shift_Del | 5 | 0.11 | MKN74 | N | 8 | 0 | 0 | N | ||||||||||||
| CREB3L2 | SQLQTNHPQ | STOMACH | 128 | p.A74fs | c.220_220delG | Frame_Shift_Del | 5 | 0.11 | MKN74 | N | 0 | 0 | 0 | Y | ||||||||||||
| CREB3L2 | SRLSTATPC | STOMACH | 77 | p.A74fs | c.220_220delG | Frame_Shift_Del | 5 | 0.11 | MKN74 | N | 3 | 0 | 0 | N | ||||||||||||
| CREB3L2 | SRQSQLQTN | STOMACH | 125 | p.A74fs | c.220_220delG | Frame_Shift_Del | 6 | 0.11 | MKN74 | N | 2 | 0 | 0 | N | ||||||||||||
| CREB3L2 | TASMTMRWK | STOMACH | 102 | p.A74fs | c.220_220delG | Frame_Shift_Del | 5 | 0.11 | MKN74 | Y | 0 | 10 | 0 | N | ||||||||||||
| CREB3L2 | TATPCARSL | STOMACH | 81 | p.A74fs | c.220_220delG | Frame_Shift_Del | 5 | 0.11 | MKN74 | Y | 12 | 10 | 0 | N | ||||||||||||
| CREB3L2 | TCLQTSLQH | STOMACH | 115 | p.A74fs | c.220_220delG | Frame_Shift_Del | 5 | 0.11 | MKN74 | N | 0 | 0 | 0 | Y | ||||||||||||
| CREB3L2 | TLPPVTASM | STOMACH | 97 | p.A74fs | c.220_220delG | Frame_Shift_Del | 5 | 0.11 | MKN74 | Y | 8 | 11 | 0 | N | ||||||||||||
| CREB3L2 | TMRWKVRNG | STOMACH | 106 | p.A74fs | c.220_220delG | Frame_Shift_Del | 6 | 0.11 | MKN74 | Y | 0 | 10 | 0 | N | ||||||||||||
| CREB3L2 | TNHPQDSFR | STOMACH | 132 | p.A74fs | c.220_220delG | Frame_Shift_Del | 6 | 0.11 | MKN74 | N | 2 | 0 | 0 | N | ||||||||||||
| CREB3L2 | TPCARSLGP | STOMACH | 83 | p.A74fs | c.220_220delG | Frame_Shift_Del | 5 | 0.11 | MKN74 | N | 0 | 0 | 0 | N | ||||||||||||
| CREB3L2 | TSLQHPSRQ | STOMACH | 119 | p.A74fs | c.220_220delG | Frame_Shift_Del | 5 | 0.11 | MKN74 | N | 0 | 0 | 0 | Y | ||||||||||||
| CREB3L2 | TSPRLSSRL | STOMACH | 71 | p.A74fs | c.220_220delG | Frame_Shift_Del | 5 | 0.11 | MKN74 | Y | 12 | 9 | 0 | N | ||||||||||||
| CREB3L2 | VRNGTCLQT | STOMACH | 111 | p.A74fs | c.220_220delG | Frame_Shift_Del | 5 | 0.11 | MKN74 | N | 2 | 0 | 11 | N | ||||||||||||
| CREB3L2 | VTASMTMRW | STOMACH | 101 | p.A74fs | c.220_220delG | Frame_Shift_Del | 6 | 0.11 | MKN74 | Y | 3 | 11 | 1 | N | ||||||||||||
| CREB3L2 | WKVRNGTCL | STOMACH | 109 | p.A74fs | c.220_220delG | Frame_Shift_Del | 5 | 0.11 | MKN74 | N | 11 | 0 | 3 | N | ||||||||||||
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