Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

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The result page of search shows exclusive peptide/epitopes generated due to mutation [Neoepitope], the tissue of origin [Tissue], position of peptide in protein [Position], number of mismatches counted by aligning mutated and normal protein sequence [Num Mismatch, percentage of cell lines with this peptide over total number of cell lines [Promiscuity %]. The immune information include CTL epitopes (Yes/No), MHC I binders, MHC II binders (both given as number of alleles) and B cell epitopes (Yes/No). For more information, please click HERE


Result Reset Search:
ProteinNeoepitopesTissuePositionProt MutationcDNA MutationMutation TypeNum MismatchPromiscuity (%)Cell LineCTLMHC INHLApredMHC IIBcell
CTNNB1DLMELEHGHSKIN6p.D11fsc.31_32insAFrame_Shift_Ins40.11HS936TN000N
CTNNB1EHGHGTRQKSKIN11p.D11fsc.31_32insAFrame_Shift_Ins60.11HS936TN000N
CTNNB1ELEHGHGTRSKIN9p.D11fsc.31_32insAFrame_Shift_Ins60.11HS936TN500N
CTNNB1GHGTRQKSGSKIN13p.D11fsc.31_32insAFrame_Shift_Ins50.11HS936TN000Y
CTNNB1HGHGTRQKSSKIN12p.D11fsc.31_32insAFrame_Shift_Ins60.11HS936TN100N
CTNNB1HGTRQKSGCSKIN14p.D11fsc.31_32insAFrame_Shift_Ins60.11HS936TN100N
CTNNB1LEHGHGTRQSKIN10p.D11fsc.31_32insAFrame_Shift_Ins60.11HS936TN000N
CTNNB1LMELEHGHGSKIN7p.D11fsc.31_32insAFrame_Shift_Ins50.11HS936TN000N
CTNNB1MELEHGHGTSKIN8p.D11fsc.31_32insAFrame_Shift_Ins50.11HS936TN700N