Cancertope
In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer
Personalized immunotherapy or Vaccine against Cancer
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The result page of search shows exclusive peptide/epitopes generated due to mutation [Neoepitope], the tissue of origin [Tissue], position of peptide in protein [Position], number of mismatches counted by aligning mutated and normal protein sequence [Num Mismatch, percentage of cell lines with this peptide over total number of cell lines [Promiscuity %]. The immune information include CTL epitopes (Yes/No), MHC I binders, MHC II binders (both given as number of alleles) and B cell epitopes (Yes/No). For more information, please click |
| Result | Search: | |||||||||||||||||||||||||
| Protein | Neoepitopes | Tissue | Position | Prot Mutation | cDNA Mutation | Mutation Type | Num Mismatch | Promiscuity (%) | Cell Line | CTL | MHC I | NHLApred | MHC II | Bcell | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| EGFR | ATQSACLRP | LARGE_INTESTINE | 558 | p.E543fs | c.1629_1629delG | Frame_Shift_Del | 5 | 0.11 | CW2 | N | 0 | 0 | 0 | N | ||||||||||||
| EGFR | AYSATQSAC | LARGE_INTESTINE | 555 | p.E543fs | c.1629_1629delG | Frame_Shift_Del | 6 | 0.11 | CW2 | N | 2 | 0 | 0 | N | ||||||||||||
| EGFR | CRGIMIFPS | OESOPHAGUS | 70 | p.T68fs | c.203_203delC | Frame_Shift_Del | 5 | 0.11 | KYSE70 | N | 2 | 0 | 0 | N | ||||||||||||
| EGFR | EITMCRGIM | OESOPHAGUS | 66 | p.T68fs | c.203_203delC | Frame_Shift_Del | 5 | 0.11 | KYSE70 | N | 2 | 0 | 0 | N | ||||||||||||
| EGFR | EVSQGSLWR | LARGE_INTESTINE | 543 | p.E543fs | c.1629_1629delG | Frame_Shift_Del | 5 | 0.11 | CW2 | Y | 5 | 9 | 0 | Y | ||||||||||||
| EGFR | GSLWRTLSA | LARGE_INTESTINE | 547 | p.E543fs | c.1629_1629delG | Frame_Shift_Del | 5 | 0.11 | CW2 | N | 3 | 0 | 0 | Y | ||||||||||||
| EGFR | ITMCRGIMI | OESOPHAGUS | 67 | p.T68fs | c.203_203delC | Frame_Shift_Del | 5 | 0.11 | KYSE70 | Y | 9 | 15 | 8 | N | ||||||||||||
| EGFR | LEITMCRGI | OESOPHAGUS | 65 | p.T68fs | c.203_203delC | Frame_Shift_Del | 5 | 0.11 | KYSE70 | N | 8 | 0 | 7 | N | ||||||||||||
| EGFR | LEVSQGSLW | LARGE_INTESTINE | 542 | p.E543fs | c.1629_1629delG | Frame_Shift_Del | 5 | 0.11 | CW2 | N | 8 | 0 | 0 | N | ||||||||||||
| EGFR | LLEVSQGSL | LARGE_INTESTINE | 541 | p.E543fs | c.1629_1629delG | Frame_Shift_Del | 5 | 0.11 | CW2 | N | 9 | 0 | 0 | N | ||||||||||||
| EGFR | MCRGIMIFP | OESOPHAGUS | 69 | p.T68fs | c.203_203delC | Frame_Shift_Del | 5 | 0.11 | KYSE70 | N | 0 | 0 | 0 | N | ||||||||||||
| EGFR | NLLEVSQGS | LARGE_INTESTINE | 540 | p.E543fs | c.1629_1629delG | Frame_Shift_Del | 5 | 0.11 | CW2 | N | 0 | 0 | 0 | N | ||||||||||||
| EGFR | QGSLWRTLS | LARGE_INTESTINE | 546 | p.E543fs | c.1629_1629delG | Frame_Shift_Del | 6 | 0.11 | CW2 | N | 0 | 0 | 0 | Y | ||||||||||||
| EGFR | SATQSACLR | LARGE_INTESTINE | 557 | p.E543fs | c.1629_1629delG | Frame_Shift_Del | 5 | 0.11 | CW2 | N | 3 | 0 | 0 | N | ||||||||||||
| EGFR | SAYSATQSA | LARGE_INTESTINE | 554 | p.E543fs | c.1629_1629delG | Frame_Shift_Del | 5 | 0.11 | CW2 | N | 4 | 0 | 0 | N | ||||||||||||
| EGFR | SLWRTLSAY | LARGE_INTESTINE | 548 | p.E543fs | c.1629_1629delG | Frame_Shift_Del | 5 | 0.11 | CW2 | Y | 7 | 15 | 0 | Y | ||||||||||||
| EGFR | SQGSLWRTL | LARGE_INTESTINE | 545 | p.E543fs | c.1629_1629delG | Frame_Shift_Del | 5 | 0.11 | CW2 | Y | 8 | 12 | 0 | N | ||||||||||||
| EGFR | TMCRGIMIF | OESOPHAGUS | 68 | p.T68fs | c.203_203delC | Frame_Shift_Del | 5 | 0.11 | KYSE70 | Y | 6 | 9 | 0 | N | ||||||||||||
| EGFR | VSQGSLWRT | LARGE_INTESTINE | 544 | p.E543fs | c.1629_1629delG | Frame_Shift_Del | 5 | 0.11 | CW2 | N | 1 | 0 | 0 | Y | ||||||||||||
| EGFR | WRTLSAYSA | LARGE_INTESTINE | 550 | p.E543fs | c.1629_1629delG | Frame_Shift_Del | 5 | 0.11 | CW2 | N | 5 | 0 | 24 | N | ||||||||||||
| EGFR | YSATQSACL | LARGE_INTESTINE | 556 | p.E543fs | c.1629_1629delG | Frame_Shift_Del | 5 | 0.11 | CW2 | N | 11 | 0 | 2 | N | ||||||||||||
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