Cancertope
In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer
Personalized immunotherapy or Vaccine against Cancer
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The result page of search shows exclusive peptide/epitopes generated due to mutation [Neoepitope], the tissue of origin [Tissue], position of peptide in protein [Position], number of mismatches counted by aligning mutated and normal protein sequence [Num Mismatch, percentage of cell lines with this peptide over total number of cell lines [Promiscuity %]. The immune information include CTL epitopes (Yes/No), MHC I binders, MHC II binders (both given as number of alleles) and B cell epitopes (Yes/No). For more information, please click |
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| Protein | Neoepitopes | Tissue | Position | Prot Mutation | cDNA Mutation | Mutation Type | Num Mismatch | Promiscuity (%) | Cell Line | CTL | MHC I | NHLApred | MHC II | Bcell | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FGFR2 | ADTPHAGRG | LARGE_INTESTINE | 456 | p.P459fs | c.1377_1378insC | Frame_Shift_Ins | 5 | 0.11 | SNUC4 | N | 0 | 0 | 0 | N | ||||||||||||
| FGFR2 | DTPHAGRGL | LARGE_INTESTINE | 457 | p.P459fs | c.1377_1378insC | Frame_Shift_Ins | 6 | 0.11 | SNUC4 | N | 6 | 0 | 0 | N | ||||||||||||
| FGFR2 | PHAGRGLRV | LARGE_INTESTINE | 459 | p.P459fs | c.1377_1378insC | Frame_Shift_Ins | 6 | 0.11 | SNUC4 | N | 0 | 0 | 0 | N | ||||||||||||
| FGFR2 | STADTPHAG | LARGE_INTESTINE | 454 | p.P459fs | c.1377_1378insC | Frame_Shift_Ins | 3 | 0.11 | SNUC4 | N | 0 | 0 | 0 | N | ||||||||||||
| FGFR2 | TADTPHAGR | LARGE_INTESTINE | 455 | p.P459fs | c.1377_1378insC | Frame_Shift_Ins | 4 | 0.11 | SNUC4 | N | 4 | 0 | 0 | N | ||||||||||||
| FGFR2 | TPHAGRGLR | LARGE_INTESTINE | 458 | p.P459fs | c.1377_1378insC | Frame_Shift_Ins | 6 | 0.11 | SNUC4 | N | 4 | 0 | 0 | N | ||||||||||||
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